Roche Platform Transition

This page compares reference ranges between the Roche and Beckman platforms for the selected category of tests. For a description of the transition from the Beckman to Roche automated chemistry platform, please see the Chemistry and Immunoassay Beckman to Roche Transition Guideline.

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Method Comparison

The comparison table contains the following columns:

Trendable?: Indicates whether both methods use the same component code and results are trendable in Epic.
Bias: The average absolute difference between Roche and Beckman results. A positive value means Roche results are higher on average.
Percent Bias: Blue shading and bars extending left indicate negative bias (Beckman higher on average); orange shading and bars extending right indicate positive bias (Roche higher on average). Longer bars indicate greater magnitude.
Slope: The slope of the linear regression of Roche onto Beckman, representing proportional bias between the methods. “Not comparable” indicates that the methods were too poorly correlated for direct patient-result comparison.
R² (Coefficient of Determination): How closely the regression fits the paired results.

These data can help when comparing results across platforms, but should not be used to convert a result directly from one method to the other.

Test Name	Beckman	Roche	Trendable?	Bias	Percent Bias	Slope	Coefficient of Determination (R²)
Aldolase	ALASE	ALASE	✅	0.219 U/L	3.09%	0.963	0.8693
Alpha 1 Antitrypsin	A1AT	A1AT	✅	-11.82 mg/dL	-5.57%	0.938	0.9887
Amylase (Total)	AYT	AYT	✅	13.2 U/L	4.64%	1.011	0.9947
Ceruloplasmin	CPLS	CPLS	✅	-1.15 mg/dL	-4.54%	1.081	0.9472
Complement C3	C3	C3	✅	3.05 mg/dL	2.12%	1.078	0.9873
Complement C4	C4	C4	✅	-7.063 mg/dL	-19.60%	0.8	0.9885
Glucose, CSF	CGLU	CGLU	✅	-2.77 mg/dL	-3.80%	0.97	0.9899
Glucose, URN	GLUPU	GLUPU	✅	28.24 mg/dL	22.47%	1.073	0.9194
Homocysteine	HMCY	HMCY	✅	-1.487 mcmol/L	-10.62%	0.932	0.8034
Interleukin 6 (IL_6)	IL6	IL6	✅	13.049 pg/mL	2.38%	1.103	0.9974
L_Lactate, Venous Plasma	VLAC	VLAC	✅			0.998
Lactate Dehydrogenase	LD	LDRD	❌	15.38 U/L	7.84%	Not comparable	0.97
Lipase	LPASE	LPASE	✅	-2.162 U/L	-2.50%	0.944	0.9876
Magnesium, Urine	MGPU	MGPU	✅	0.022 mg/dL	0.29%	0.986	0.9597
Myoglobin	MYO	MYO	✅	18.5 ng/mL	7.88%	1.132	0.992
Phosphate, URN	PPU	PPU	✅	-1.52 mg/dL	-2.12%	0.947	0.9936
Protein (Total), CSF	CTP	CTP	✅	-15.39 mg/dL	-16.18%	0.935	0.9528
Pseudocholinesterase	PCASE	PCASE	✅	-41.5 U/L	-0.60%	1.051	0.9749
Rheumatoid Factor	RF	RF	✅	-2 IU/mL	-3.46%	0.96	0.9836
Urea Nitrogen/Unit, URN	UNPU	UNPU	✅	18.9 mg/dL	3.60%	0.972	0.9124
Uric Acid	URIC	URIC	✅	-0.683 mg/dL	-13.37%	0.995	0.9103
Uric Acid, URN	URIPU	URIPU	✅	-7.045 mg/dL	-19.61%	0.862	0.9107
Vitamin B12 (Cobalamin)	VITB12	VITB12	✅	299.9 pg/mL	53.40%	1.509	0.996

Reference Ranges

Name

Beckman

Roche

Aldolase

Name: Aldolase
Mnemonic: ALASE
Units: U/L
Method Code: HAUTO

Female		Male
Age	Range	Age	Range
16y-	1-8	16y-	1-8

Effective date: 08/31/2026

Name: Aldolase
Mnemonic: ALASE
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-17y	0-14	0-17y	0-14
18y-	0-7	18y-	0-7

Effective date: 09/14/2026

Alpha 1 Antitrypsin

Name: Alpha 1 Antitrypsin
Mnemonic: A1AT
Units: mg/dL
Method Code: UAUTO

Female		Male
Age	Range	Age	Range
0-	84-218	0-	84-218

Effective date: 08/31/2026

Name: Alpha 1 Antitrypsin
Mnemonic: A1AT
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	90-200	0-	90-200

Effective date: 09/14/2026

Amylase (Total)

Name: Amylase (Total)
Mnemonic: AYT
Units: U/L
Method Code: HAUTO

Female		Male
Age	Range	Age	Range
0-	27-106	0-	27-106

Effective date: 08/31/2026

Name: Amylase (Total)
Mnemonic: AYT
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	37-132	0-	37-132

Effective date: 09/14/2026

Ceruloplasmin

Name: Ceruloplasmin
Mnemonic: CPLS
Units: mg/dL
Method Code: UAUTO

Female		Male
Age	Range	Age	Range
0-	18.0-58.0	0-	18.0-58.0

Effective date: 08/31/2026

Name: Ceruloplasmin
Mnemonic: CPLS
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	16-45	0-	15-30

Effective date: 09/14/2026

Complement C3

Name: Complement C3
Mnemonic: C3
Units: mg/dL
Method Code: UAUTO

Female		Male
Age	Range	Age	Range
0-	87-200	0-	87-200

Effective date: 08/31/2026

Name: Complement C3
Mnemonic: C3
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	90-180	0-	90-180

Effective date: 09/14/2026

Complement C4

Name: Complement C4
Mnemonic: C4
Units: mg/dL
Method Code: UAUTO

Female		Male
Age	Range	Age	Range
0-	13-50	0-	13-50

Effective date: 08/31/2026

Name: Complement C4
Mnemonic: C4
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	10-40	0-	10-40

Effective date: 09/14/2026

Glucose, CSF

Name: Glucose, CSF
Mnemonic: CGLU
Units: mg/dL
Method Code: HAUTO

Female		Male
Age	Range	Age	Range
0-	40-80	0-	40-80

Effective date: 08/31/2026

Name: Glucose, CSF
Mnemonic: CGLU
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	40-80	0-	40-80

Effective date: 09/14/2026

Glucose, URN

Name: Glucose, URN
Mnemonic: GLUPU
Units: mg/dL
Method Code: HAUTO

Female		Male
Age	Range	Age	Range
0-	0-10	0-	0-10

Effective date: 08/31/2026

Name: Glucose, URN
Mnemonic: GLUPU
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0-10	0-	0-10

Effective date: 09/14/2026

Homocysteine

Name: Homocysteine
Mnemonic: HMCY
Units: mcmol/L
Method Code: UAUTO

Female		Male
Age	Range	Age	Range
0-19y	0.0-15.0	0-19y	0.0-15.0
20y-59y	4.6-12.5	20y-59y	6.2-15.0
60y-	6.2-15.0	60y-

Effective date: 08/31/2026

Name: Homocysteine
Mnemonic: HMCY
Units: mcmol/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0-16	0-	0-16

Effective date: 09/14/2026

Interleukin 6 (IL_6)

Name: Interleukin 6 (IL_6)
Mnemonic: IL6
Units: pg/mL
Method Code: HAUTO

Female		Male
Age	Range	Age	Range
18y-	0-6	18y-	0-6

Effective date: 08/31/2026

Name: Interleukin 6 (IL_6)
Mnemonic: IL6
Units: pg/mL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0-7	0-	0-7

Effective date: 09/14/2026

L_Lactate, Venous Plasma

Name: L_Lactate, Venous Plasma
Mnemonic: VLAC
Units: mmol/L
Method Code: UAUTO

Female		Male
Age	Range	Age	Range
0-	0.5-2.2	0-	0.5-2.2

Effective date: 08/31/2026

Name: L_Lactate, Venous Plasma
Mnemonic: VLAC
Units: mmol/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0.5-2.2	0-	0.5-2.2

Effective date: 09/14/2026

Lactate Dehydrogenase

Name: Lactate Dehydrogenase (Beckman)
Mnemonic: LD
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	<210	0-	<210

Effective date: 03/01/2015

Name: Lactate Dehydrogenase (Roche)
Mnemonic: LDRD
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0-225	0-	0-225

Effective date: 09/02/2026

Lipase

Name: Lipase
Mnemonic: LPASE
Units: U/L
Method Code: HAUTO

Female		Male
Age	Range	Age	Range
0-	<70	0-	<70

Effective date: 08/31/2026

Name: Lipase
Mnemonic: LPASE
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0-70	0-	0-70

Effective date: 09/14/2026

Magnesium, Urine

Name: Magnesium, Urine
Mnemonic: MGPU
Units: mg/dL
Method Code: UAUTO
Effective date: 08/31/2026

Name: Magnesium, Urine
Mnemonic: MGPU
Units: mg/dL
Method Code: default
Effective date: 09/14/2026

Myoglobin

Name: Myoglobin
Mnemonic: MYO
Units: ng/mL
Method Code: HAUTO

Female		Male
Age	Range	Age	Range
0-	14-66	0-	17-106

Effective date: 08/31/2026

Name: Myoglobin
Mnemonic: MYO
Units: ng/mL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0-58	0-	0-72

Effective date: 09/14/2026

Phosphate, URN

Name: Phosphate, URN
Mnemonic: PPU
Units: mg/dL
Method Code: UAUTO
Effective date: 08/31/2026

Name: Phosphate, URN
Mnemonic: PPU
Units: mg/dL
Method Code: default
Effective date: 09/14/2026

Protein (Total), CSF

Name: Protein (Total), CSF
Mnemonic: CTP
Units: mg/dL
Method Code: HAUTO

Female		Male
Age	Range	Age	Range
0-	15-45	0-	15-45

Effective date: 08/31/2026

Name: Protein (Total), CSF
Mnemonic: CTP
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	15-45	0-	15-45

Effective date: 09/14/2026

Pseudocholinesterase

Name: Pseudocholinesterase
Mnemonic: PCASE
Units: U/L
Method Code: HAUTO

Female		Male
Age	Range	Age	Range
0-	4900-11900	0-	4900-11900

Effective date: 08/31/2026

Name: Pseudocholinesterase
Mnemonic: PCASE
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	5320-12920	0-	5320-12920

Effective date: 09/14/2026

Rheumatoid Factor

Name: Rheumatoid Factor
Mnemonic: RF
Units: IU/mL
Method Code: UAUTO

Female		Male
Age	Range	Age	Range
0-	<15	0-	<15

Effective date: 08/31/2026

Name: Rheumatoid Factor
Mnemonic: RF
Units: IU/mL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0-14	0-	0-14

Effective date: 09/14/2026

Urea Nitrogen/Unit, URN

Name: Urea Nitrogen/Unit, URN
Mnemonic: UNPU
Units: mg/dL
Method Code: HAUTO
Effective date: 08/31/2026

Name: Urea Nitrogen/Unit, URN
Mnemonic: UNPU
Units: mg/dL
Method Code: default
Effective date: 09/14/2026

Uric Acid

Name: Uric Acid
Mnemonic: URIC
Units: mg/dL
Method Code: HAUTO

Female		Male
Age	Range	Age	Range
0-	2.6-6.8	0-	3.9-7.6

Effective date: 08/31/2026

Name: Uric Acid
Mnemonic: URIC
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	2.4-6.2	0-	3.4-7.0

Effective date: 09/14/2026

Uric Acid, URN

Name: Uric Acid, URN
Mnemonic: URIPU
Units: mg/dL
Method Code: HAUTO
Effective date: 08/31/2026

Name: Uric Acid, URN
Mnemonic: URIPU
Units: mg/dL
Method Code: default
Effective date: 09/14/2026

Vitamin B12 (Cobalamin)

Name: Vitamin B12 (Cobalamin)
Mnemonic: VITB12
Units: pg/mL
Method Code: HAUTO

Female		Male
Age	Range	Age	Range
0-	180-914	0-	180-914

Effective date: 08/31/2026

Name: Vitamin B12 (Cobalamin)
Mnemonic: VITB12
Units: pg/mL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	232-1245	0-	232-1245

Effective date: 09/14/2026