Roche Platform Transition

This page compares reference ranges between the Roche and Beckman platforms for the selected category of tests. For a description of the transition from the Beckman to Roche automated chemistry platform, please see the Chemistry and Immunoassay Beckman to Roche Transition Guideline.

All BMP Liver Kidney Lipids Endocrine Tumor Marker Cardiac Misc Drugs Heme

Method Comparison

The comparison table contains the following columns:

  • Trendable?: Indicates whether both methods use the same component code and results are trendable in Epic.
  • Bias: The average absolute difference between Roche and Beckman results. A positive value means Roche results are higher on average.
  • Percent Bias: Blue shading and bars extending left indicate negative bias (Beckman higher on average); orange shading and bars extending right indicate positive bias (Roche higher on average). Longer bars indicate greater magnitude.
  • Slope: The slope of the linear regression of Roche onto Beckman, representing proportional bias between the methods. “Not comparable” indicates that the methods were too poorly correlated for direct patient-result comparison.
  • R2 (Coefficient of Determination): How closely the regression fits the paired results.

These data can help when comparing results across platforms, but should not be used to convert a result directly from one method to the other.

Test Name Beckman Roche Trendable? Bias Percent Bias Slope Coefficient of Determination (R2)
Aldolase ALASE ALASE ✅ 0.219 U/L 3.09% 0.963 0.8693
Alpha 1 Antitrypsin A1AT A1AT ✅ -11.82 mg/dL -5.57% 0.938 0.9887
Amylase (Total) AYT AYT ✅ 13.2 U/L 4.64% 1.011 0.9947
Ceruloplasmin CPLS CPLS ✅ -1.15 mg/dL -4.54% 1.081 0.9472
Complement C3 C3 C3 ✅ 3.05 mg/dL 2.12% 1.078 0.9873
Complement C4 C4 C4 ✅ -7.063 mg/dL -19.60% 0.8 0.9885
Glucose, CSF CGLU CGLU ✅ -2.77 mg/dL -3.80% 0.97 0.9899
Glucose, URN GLUPU GLUPU ✅ 28.24 mg/dL 22.47% 1.073 0.9194
Homocysteine HMCY HMCY ✅ -1.487 mcmol/L -10.62% 0.932 0.8034
Interleukin 6 (IL_6) IL6 IL6 ✅ 13.049 pg/mL 2.38% 1.103 0.9974
L_Lactate, Venous Plasma VLAC VLAC ✅ 0.998
Lactate Dehydrogenase LD LDRD ❌ 15.38 U/L 7.84% 1.26 0.97
Lipase LPASE LPASE ✅ -2.162 U/L -2.50% 0.944 0.9876
Magnesium, Urine MGPU MGPU ✅ 0.022 mg/dL 0.29% 0.986 0.9597
Myoglobin MYO MYO ✅ 18.5 ng/mL 7.88% 1.132 0.992
Phosphate, URN PPU PPU ✅ -1.52 mg/dL -2.12% 0.947 0.9936
Protein (Total), CSF CTP CTP ✅ -15.39 mg/dL -16.18% 0.935 0.9528
Pseudocholinesterase PCASE PCASE ✅ -41.5 U/L -0.60% 1.051 0.9749
Rheumatoid Factor RF RF ✅ -2 IU/mL -3.46% 0.96 0.9836
Urea Nitrogen/Unit, URN UNPU UNPU ✅ 18.9 mg/dL 3.60% 0.972 0.9124
Uric Acid URIC URIC ✅ -0.683 mg/dL -13.37% 0.995 0.9103
Uric Acid, URN URIPU URIPU ✅ -7.045 mg/dL -19.61% 0.862 0.9107
Vitamin B12 (Cobalamin) VITB12 VITB12 ✅ 299.9 pg/mL 53.40% 1.509 0.996

Reference Ranges

Name
Beckman
Roche
Aldolase
Name: Aldolase
Mnemonic: ALASE
Units: U/L (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0-17y 0-14 0-17y 0-14
18y- 0-7 18y- 0-7
Effective date: 09/14/2026
Name: Aldolase
Mnemonic: ALASE
Alpha 1 Antitrypsin
Name: Alpha 1 Antitrypsin
Mnemonic: A1AT
Units: mg/dL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 90-200 0- 90-200
Effective date: 09/14/2026
Name: Alpha 1 Antitrypsin
Mnemonic: A1AT
Amylase (Total)
Name: Amylase (Total)
Mnemonic: AYT
Units: U/L (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 37-132 0- 37-132
Effective date: 09/14/2026
Name: Amylase (Total)
Mnemonic: AYT
Ceruloplasmin
Name: Ceruloplasmin
Mnemonic: CPLS
Units: mg/dL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 16-45 0- 15-30
Effective date: 09/14/2026
Name: Ceruloplasmin
Mnemonic: CPLS
Complement C3
Name: Complement C3
Mnemonic: C3
Units: mg/dL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 90-180 0- 90-180
Effective date: 09/14/2026
Name: Complement C3
Mnemonic: C3
Complement C4
Name: Complement C4
Mnemonic: C4
Units: mg/dL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 10-40 0- 10-40
Effective date: 09/14/2026
Name: Complement C4
Mnemonic: C4
Glucose, CSF
Name: Glucose, CSF
Mnemonic: CGLU
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 40-80 0- 40-80
Effective date: 09/14/2026
Name: Glucose, CSF
Mnemonic: CGLU
Units: mg/dL
Method Code: FMPRO1
Female Male
AgeRange AgeRange
0- 40-80 0- 40-80
Effective date: 03/12/2026
Glucose, URN
Name: Glucose, URN
Mnemonic: GLUPU
Units: mg/dL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 0-10 0- 0-10
Effective date: 09/14/2026
Name: Glucose, URN
Mnemonic: GLUPU
Homocysteine
Name: Homocysteine
Mnemonic: HMCY
Units: mcmol/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0-16 0- 0-16
Effective date: 09/14/2026
Name: Homocysteine
Mnemonic: HMCY
Units: mcmol/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0-16 0- 0-16
Effective date: 09/14/2026
Interleukin 6 (IL_6)
Name: Interleukin 6 (IL_6)
Mnemonic: IL6
Units: pg/mL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 0-7 0- 0-7
Effective date: 09/14/2026
Name: Interleukin 6 (IL_6)
Mnemonic: IL6
L_Lactate, Venous Plasma
Name: L_Lactate, Venous Plasma
Mnemonic: VLAC
Units: mmol/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0.5-2.2 0- 0.5-2.2
Effective date: 09/14/2026
Name: L_Lactate, Venous Plasma
Mnemonic: VLAC
Units: mmol/L
Method Code: FMPRO1
Female Male
AgeRange AgeRange
0- 0.5-2.2 0- 0.5-2.2
Effective date: 03/12/2026
Lactate Dehydrogenase
Name: Lactate Dehydrogenase (Beckman)
Mnemonic: LD
Units: U/L
Method Code: default
Female Male
AgeRange AgeRange
0- <210 0- <210
Effective date: 03/01/2015
Name: Lactate Dehydrogenase (Roche)
Mnemonic: LDRD
Units: U/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0-225 0- 0-225
Effective date: 09/02/2026
Lipase
Name: Lipase
Mnemonic: LPASE
Units: U/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0-70 0- 0-70
Effective date: 09/14/2026
Name: Lipase
Mnemonic: LPASE
Units: U/L
Method Code: FMPRO1
Female Male
AgeRange AgeRange
0- <71 0- <71
Effective date: 03/12/2026
Magnesium, Urine
Name: Magnesium, Urine
Mnemonic: MGPU
Units: mg/dL (units differ between platforms)
Method Code: default Effective date: 09/14/2026
Name: Magnesium, Urine
Mnemonic: MGPU
Myoglobin
Name: Myoglobin
Mnemonic: MYO
Units: ng/mL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 0-58 0- 0-72
Effective date: 09/14/2026
Name: Myoglobin
Mnemonic: MYO
Phosphate, URN
Name: Phosphate, URN
Mnemonic: PPU
Units: mg/dL (units differ between platforms)
Method Code: default Effective date: 09/14/2026
Name: Phosphate, URN
Mnemonic: PPU
Protein (Total), CSF
Name: Protein (Total), CSF
Mnemonic: CTP
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 15-45 0- 15-45
Effective date: 09/14/2026
Name: Protein (Total), CSF
Mnemonic: CTP
Units: mg/dL
Method Code: FMPRO1
Female Male
AgeRange AgeRange
0- 15-45 0- 15-45
Effective date: 03/12/2026
Pseudocholinesterase
Name: Pseudocholinesterase
Mnemonic: PCASE
Units: U/L (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 5320-12920 0- 5320-12920
Effective date: 09/14/2026
Name: Pseudocholinesterase
Mnemonic: PCASE
Rheumatoid Factor
Name: Rheumatoid Factor
Mnemonic: RF
Units: IU/mL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 0-14 0- 0-14
Effective date: 09/14/2026
Name: Rheumatoid Factor
Mnemonic: RF
Urea Nitrogen/Unit, URN
Name: Urea Nitrogen/Unit, URN
Mnemonic: UNPU
Units: mg/dL (units differ between platforms)
Method Code: default Effective date: 09/14/2026
Name: Urea Nitrogen/Unit, URN
Mnemonic: UNPU
Uric Acid
Name: Uric Acid
Mnemonic: URIC
Units: mg/dL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 2.4-6.2 0- 3.4-7.0
Effective date: 09/14/2026
Name: Uric Acid
Mnemonic: URIC
Uric Acid, URN
Name: Uric Acid, URN
Mnemonic: URIPU
Units: mg/dL (units differ between platforms)
Method Code: default Effective date: 09/14/2026
Name: Uric Acid, URN
Mnemonic: URIPU
Vitamin B12 (Cobalamin)
Name: Vitamin B12 (Cobalamin)
Mnemonic: VITB12
Units: pg/mL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 232-1245 0- 232-1245
Effective date: 09/14/2026
Name: Vitamin B12 (Cobalamin)
Mnemonic: VITB12