Roche Platform Transition

This page compares reference ranges between the Roche and Beckman platforms for the selected category of tests. For a description of the transition from the Beckman to Roche automated chemistry platform, please see the Chemistry and Immunoassay Beckman to Roche Transition Guideline.

All BMP Liver Kidney Misc

Method Comparison

The slope of the linear regression of Roche onto Beckman represents the proportional bias between the two methods (i.e., the proportional change going from Beckman to Roche). The mean bias is expressed as a % or an absolute bias depending on whether there is a proportional bias between Beckman and Roche or a constant bias. A positive mean bias means that Roche results are higher than Beckman results, on average. While it is not recommended to use this information to convert one result directly to the other, the data will help when comparing results across platforms.

Tests with significantly different performance characteristics are reported using different component names and are not trendable in Epic. Certain analytes, labeled "Not comparable," were so poorly correlated that results from Beckman and Roche should not be directly compared for the care of patients. Trends of measurements on the same instrument platform for the same patient over time are interpretable.

Test Name Beckman Code Roche Code Same code/Trendable? Bias Percent Bias Slope of the Linear Regression (Roche vs. Beckman) Coefficient of Determination (R2)
Urea Nitrogen BUN BUN ✅ -0.55 mg/dL -3.30% 0.98  1.00 
Calcium CA CA ✅ -0.09 mg/dL -0.90% 0.95  0.99 
Chloride CL CL ✅ -2.15 mEq/L  -2.10% 1.01  1.00 
Carbon Dioxide CO2 CO2 ✅ -0.70 mEq/L -3.20% 0.85  0.95 
Creatinine CRE CRE ✅ 0.02 mg/dL 2.90% 0.98  1.00 
Anion Gap IGAP IGAP ✅ 2.90 units 22.80% 1.01  0.94 
Potassium K K ✅ 0.06 mEq/L 1.50% 0.99  1.00 
Sodium NA NA ✅ <0.2 mEq/L 0.10% 0.99  1.00 

Reference Ranges

Name
Beckman
Roche
Urea Nitrogen
Name: Urea Nitrogen
Mnemonic: BUN
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 8-21 0- 8-21
Effective date: 03/01/2015
Name: Urea Nitrogen
Mnemonic: BUN
Units: mg/dL
Method Code: F3PUR1
Female Male
AgeRange AgeRange
0- 6-20 0- 6-20
Effective date: 12/23/2025
Calcium
Name: Calcium
Mnemonic: CA
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 8.9-10.2 0- 8.9-10.2
Effective date: 03/01/2015
Name: Calcium
Mnemonic: CA
Units: mg/dL
Method Code: F3PUR1
Female Male
AgeRange AgeRange
0- 8.8-10.2 0- 8.8-10.2
Effective date: 12/23/2025
Chloride
Name: Chloride
Mnemonic: CL
Units: mEq/L
Method Code: default
Female Male
AgeRange AgeRange
0- 98-108 0- 98-108
Effective date: 03/01/2015
Name: Chloride
Mnemonic: CL
Units: mEq/L
Method Code: F3PUR1
Female Male
AgeRange AgeRange
0- 98-107 0- 98-107
Effective date: 12/23/2025
Carbon Dioxide
Name: Carbon Dioxide, Total
Mnemonic: CO2
Units: mEq/L
Method Code: default
Female Male
AgeRange AgeRange
0- 22-32 0- 22-32
Effective date: 03/01/2015
Name: Carbon Dioxide, Total
Mnemonic: CO2
Units: mEq/L
Method Code: F3PUR1
Female Male
AgeRange AgeRange
0- 22-29 0- 22-29
Effective date: 12/23/2025
Creatinine
Name: Creatinine
Mnemonic: CRE
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0-17y 0.20-1.10 0-17y 0.20-1.10
18y- 0.38-1.02 18y- 0.51-1.18
Effective date: 03/01/2015
Name: Creatinine
Mnemonic: CRE
Units: mg/dL
Method Code: F3PUR1
Female Male
AgeRange AgeRange
0- 0.5-1.0 0- 0.7-1.2
Effective date: 12/23/2025
Anion Gap
Name: Anion Gap
Mnemonic: IGAP
Units: not defined
Method Code: default
Female Male
AgeRange AgeRange
0- 4-12 0- 4-12
Effective date: 03/01/2015
Name: Anion Gap
Mnemonic: IGAP
Units: not defined
Method Code: FMPRO1
Female Male
AgeRange AgeRange
0- 7-15 0- 7-15
Effective date: 02/20/2026
Potassium
Name: Potassium
Mnemonic: K
Units: mEq/L
Method Code: default
Female Male
AgeRange AgeRange
0- 3.6-5.2 0- 3.6-5.2
Effective date: 03/01/2015
Name: Potassium
Mnemonic: K
Units: mEq/L
Method Code: F3PUR1
Female Male
AgeRange AgeRange
0- 3.5-5.1 0- 3.5-5.1
Effective date: 12/23/2025
Sodium
Name: Sodium
Mnemonic: NA
Units: mEq/L
Method Code: default
Female Male
AgeRange AgeRange
0- 135-145 0- 135-145
Effective date: 03/01/2015
Name: Sodium
Mnemonic: NA
Units: mEq/L
Method Code: F3PUR1
Female Male
AgeRange AgeRange
0- 136-145 0- 136-145
Effective date: 12/23/2025