Roche Platform Transition

This page compares reference ranges between the Roche and Beckman platforms for the selected category of tests. For a description of the transition from the Beckman to Roche automated chemistry platform, please see the Chemistry and Immunoassay Beckman to Roche Transition Guideline.

All BMP Liver Kidney Endocrine Misc

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Method Comparison

The comparison table contains the following columns:

Trendable?: Indicates whether both methods use the same component code and results are trendable in Epic.
Bias: The average absolute difference between Roche and Beckman results. A positive value means Roche results are higher on average.
Percent Bias: Blue shading and bars extending left indicate negative bias (Beckman higher on average); orange shading and bars extending right indicate positive bias (Roche higher on average). Longer bars indicate greater magnitude.
Slope: The slope of the linear regression of Roche onto Beckman, representing proportional bias between the methods. “Not comparable” indicates that the methods were too poorly correlated for direct patient-result comparison.
R² (Coefficient of Determination): How closely the regression fits the paired results.

These data can help when comparing results across platforms, but should not be used to convert a result directly from one method to the other.

Test Name	Beckman	Roche	Trendable?	Bias	Percent Bias	Slope	Coefficient of Determination (R²)
Albumin	ALB	ALB	✅	0.122 g/dL	3.14%	0.965	0.992
Alkaline Phosphatase (Total)	ALK	ALK	✅	1.11 U/L	0.72%	1.01	0.9967
ALT	ALT	ALTRD	❌	15.916 U/L	33.30%	1.307	0.9896
Anion Gap	IGAP	IGAP	✅	2.90 units	22.80%	1.01	0.94
AST	AST	ASTRD	❌	26.77 U/L	25.01%	1.233	0.9964
Calcium	CA	CA	✅	-0.409 mg/dL	-5.02%	1.167	0.9705
Carbon Dioxide, Total	CO2	CO2	✅	-0.822 mEq/L	-5.01%	1.038	0.9022
Chloride	CL	CL	✅	-2.57 mEq/L	-2.47%	1.126	0.9869
Creatinine	CRE	CRE	✅	-0.0376 mg/dL	-0.73%	0.97	0.9957
Direct Bilirubin	BILD	BILDRD	❌	0.2022 mg/dL	7.84%	1.098	0.9701
Lactate Dehydrogenase	LD	LDRD	❌	15.38 U/L	7.84%	1.26	0.97
Magnesium	MG	MG	✅	-0.3237 mg/dL	-14.37%	1.154	0.9495
Phosphate	P	P	✅	-0.038 mg/dL	-0.81%	1.021	0.9907
Potassium	K	K	✅	-0.064 mEq/L	-1.53%	1.118	0.9897
Sodium	NA	NA	✅	-2.82 mEq/L	-1.98%	1.089	0.9481
Total Bilirubin	BIL	BILRD	❌	-0.3113 mg/dL	-6.30%	0.927	0.9706
Total Protein	TP	TPRD	❌	-0.365 g/dL	-5.61%	1.022	0.9228
Urea Nitrogen	BUN	BUN	✅	-2.567 mg/dL	-8.02%	0.943	0.9983
Uric Acid	URIC	URIC	✅	-0.683 mg/dL	-13.37%	0.995	0.9103

Reference Ranges

Name

Beckman

Roche

Albumin

Name: Albumin
Mnemonic: ALB
Units: g/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	3.9-5.2	0-	3.9-5.2

Effective date: 09/14/2026

Name: Albumin
Mnemonic: ALB
Units: g/dL
Method Code: EVPUR1

Female		Male
Age	Range	Age	Range
0-	3.9-5.2	0-	3.9-5.2

Effective date: 02/20/2026

Alkaline Phosphatase (Total)

Name: Alkaline Phosphatase (Total)
Mnemonic: ALK
Units: U/L (units differ between platforms)
Method Code: default

Female		Male
Age	Range	Age	Range
0-	35-104	0-	40-129

Effective date: 09/14/2026

Name: Alkaline Phosphatase (Total)
Mnemonic: ALK

ALT

Name: ALT (Beckman)
Mnemonic: ALT
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	7-33
		0-49y	10-64
		50y-	10-48

Effective date: 03/01/2015

Name: ALT (Roche)
Mnemonic: ALTRD
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0-43	0-	0-63

Effective date: 09/02/2026

Anion Gap

Name: Anion Gap
Mnemonic: IGAP
Units: not defined
Method Code: default

Female		Male
Age	Range	Age	Range
0-	7-15	0-	7-15

Effective date: 09/14/2026

Name: Anion Gap
Mnemonic: IGAP
Units: not defined
Method Code: EVPUR1

Female		Male
Age	Range	Age	Range
0-	7-15	0-	7-15

Effective date: 02/20/2026

AST

Name: AST (Beckman)
Mnemonic: AST
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	9-38	0-	9-38

Effective date: 03/01/2015

Name: AST (Roche)
Mnemonic: ASTRD
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0-35	0-	0-50

Effective date: 09/02/2026

Calcium

Name: Calcium
Mnemonic: CA
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	8.8-10.2	0-	8.8-10.2

Effective date: 09/14/2026

Name: Calcium
Mnemonic: CA
Units: mg/dL
Method Code: EVPUR1

Female		Male
Age	Range	Age	Range
0-	8.8-10.2	0-	8.8-10.2

Effective date: 02/19/2026

Carbon Dioxide, Total

Name: Carbon Dioxide, Total
Mnemonic: CO2
Units: mEq/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	22-29	0-	22-29

Effective date: 09/14/2026

Name: Carbon Dioxide, Total
Mnemonic: CO2
Units: mEq/L
Method Code: EVPUR1

Female		Male
Age	Range	Age	Range
0-	22-29	0-	22-29

Effective date: 02/20/2026

Chloride

Name: Chloride
Mnemonic: CL
Units: mEq/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	98-107	0-	98-107

Effective date: 09/14/2026

Name: Chloride
Mnemonic: CL
Units: mEq/L
Method Code: EVPUR1

Female		Male
Age	Range	Age	Range
0-	98-107	0-	98-107

Effective date: 02/19/2026

Creatinine

Name: Creatinine
Mnemonic: CRE
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0.50-1.00	0-	0.70-1.20

Effective date: 09/14/2026

Name: Creatinine
Mnemonic: CRE
Units: mg/dL
Method Code: EVPUR1

Female		Male
Age	Range	Age	Range
0-	0.50-1.00	0-	0.70-1.20

Effective date: 02/20/2026

Direct Bilirubin

Name: Direct Bilirubin (Beckman)
Mnemonic: BILD
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0.0-0.3	0-	0.0-0.3

Effective date: 03/01/2015

Name: Direct Bilirubin (Roche)
Mnemonic: BILDRD
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0.0-0.4	0-	0.0-0.4

Effective date: 09/02/2026

Lactate Dehydrogenase

Name: Lactate Dehydrogenase (Beckman)
Mnemonic: LD
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	<210	0-	<210

Effective date: 03/01/2015

Name: Lactate Dehydrogenase (Roche)
Mnemonic: LDRD
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0-225	0-	0-225

Effective date: 09/02/2026

Magnesium

Name: Magnesium
Mnemonic: MG
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	1.6-2.6	0-	1.6-2.6

Effective date: 09/14/2026

Name: Magnesium
Mnemonic: MG
Units: mg/dL
Method Code: EVPUR1

Female		Male
Age	Range	Age	Range
0-	1.6-2.6	0-	1.6-2.6

Effective date: 02/10/2026

Phosphate

Name: Phosphate
Mnemonic: P
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	2.5-4.5	0-	2.5-4.5

Effective date: 09/14/2026

Name: Phosphate
Mnemonic: P
Units: mg/dL
Method Code: EVPUR1

Female		Male
Age	Range	Age	Range
0-	2.5-4.5	0-	2.5-4.5

Effective date: 02/20/2026

Potassium

Name: Potassium
Mnemonic: K
Units: mEq/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	3.5-5.1	0-	3.5-5.1

Effective date: 09/14/2026

Name: Potassium
Mnemonic: K
Units: mEq/L
Method Code: EVPUR1

Female		Male
Age	Range	Age	Range
0-	3.5-5.1	0-	3.5-5.1

Effective date: 02/10/2026

Sodium

Name: Sodium
Mnemonic: NA
Units: mEq/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	136-145	0-	136-145

Effective date: 09/14/2026

Name: Sodium
Mnemonic: NA
Units: mEq/L
Method Code: EVPUR1

Female		Male
Age	Range	Age	Range
0-	136-145	0-	136-145

Effective date: 02/10/2026

Total Bilirubin

Name: Total Bilirubin (Beckman)
Mnemonic: BIL
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-29d	0.2-1.3	0-29d	0.2-1.3
1m-	0.2-1.3	1m-	0.2-1.3

Effective date: 03/01/2015

Name: Total Bilirubin (Roche)
Mnemonic: BILRD
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-29d	0.0-1.1	0-29d	0.0-1.1
1m-	0.0-1.1	1m-	0.0-1.1

Effective date: 09/02/2026

Total Protein

Name: Total Protein (Beckman)
Mnemonic: TP
Units: g/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	6.0-8.2	0-	6.0-8.2

Effective date: 03/01/2015

Name: Total Protein (Roche)
Mnemonic: TPRD
Units: g/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	6.4-8.3	0-	6.4-8.3

Effective date: 09/02/2026

Urea Nitrogen

Name: Urea Nitrogen
Mnemonic: BUN
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	6-20	0-	6-20

Effective date: 09/14/2026

Name: Urea Nitrogen
Mnemonic: BUN
Units: mg/dL
Method Code: EVPUR1

Female		Male
Age	Range	Age	Range
0-	6-20	0-	6-20

Effective date: 02/20/2026

Uric Acid

Name: Uric Acid
Mnemonic: URIC
Units: mg/dL (units differ between platforms)
Method Code: default

Female		Male
Age	Range	Age	Range
0-	2.4-6.2	0-	3.4-7.0

Effective date: 09/14/2026

Name: Uric Acid
Mnemonic: URIC