Roche Platform Transition

This page compares reference ranges between the Roche and Beckman platforms for the selected category of tests. For a description of the transition from the Beckman to Roche automated chemistry platform, please see the Chemistry and Immunoassay Beckman to Roche Transition Guideline.

All BMP Liver Kidney Lipids Endocrine Tumor Marker Cardiac Misc Drugs Heme

Method Comparison

The comparison table contains the following columns:

  • Trendable?: Indicates whether both methods use the same component code and results are trendable in Epic.
  • Bias: The average absolute difference between Roche and Beckman results. A positive value means Roche results are higher on average.
  • Percent Bias: Blue shading and bars extending left indicate negative bias (Beckman higher on average); orange shading and bars extending right indicate positive bias (Roche higher on average). Longer bars indicate greater magnitude.
  • Slope: The slope of the linear regression of Roche onto Beckman, representing proportional bias between the methods. “Not comparable” indicates that the methods were too poorly correlated for direct patient-result comparison.
  • R2 (Coefficient of Determination): How closely the regression fits the paired results.

These data can help when comparing results across platforms, but should not be used to convert a result directly from one method to the other.

Test Name Beckman Roche Trendable? Bias Percent Bias Slope Coefficient of Determination (R2)
Acetaminophen (Tylenol) TYL TYL ✅ -6.484 mcg/mL -6.32% 0.893 0.9737
Alcohol (Ethyl) ETOH ETOH ✅ 8.09 mg/dL 4.55% 1.114 0.9872
Alcohol (Ethyl), URN UETOH UETOH ✅ -0.05 mg/dL -0.04% 0.998 0.9971
Amikacin, Random Level AMIKAR AMIKAR ✅ 0.9031 mcg/mL 4.54% 1.074 0.9828
Carbamazepine (Tegretol) CBAM CBAM ✅ 0.648 mcg/mL 6.16% 1.094 0.9863
Digoxin DIG DIG ✅ -0.3064 ng/mL -9.74% 0.928 0.9884
Gentamicin, Random Level GENTAR GENTAR ✅ -0.564 mcg/mL -8.60% Not comparable 0.995
Lamotrigine LAMOT LAMOT ✅ -0.865 mcg/mL -13.14% 0.868 0.9814
Levetiracetam LEVET LEVET ✅ -2.127 mcg/mL -7.05% 0.99 0.9666
Lidocaine LIDO LIDO ✅ -1.637 mcg/mL -31.60% 0.739 0.9665
Lithium LI LI ✅ 0.05914 mEq/L 6.22% 1.002 0.9997
Mycophenolic Acid MPA MPA ✅ -0.405 mcg/mL -11.55% 0.864 0.9557
Phenobarbital PHNO PHNO ✅ -0.028 mcg/mL -0.14% 0.955 0.9924
Phenytoin (Dilantin) DIL DIL ✅ 1.372 mcg/mL 7.12% 0.959 0.9815
Salicylate ASA ASA ✅ -0.031 mg/dL -0.09% 0.923 0.9872
Theophylline THEO THEO ✅ 0.823 mcg/mL 6.27% 0.994 0.9939
Tobramycin, Random Level TOBRAR TOBRAR ✅ -0.2708 mcg/mL -4.94% 0.952 0.9961
Valproic Acid (Depakene) VPA VPA ✅ -1.205 mcg/mL -2.53% 0.99 0.9969
Vancomycin, Random Level VANCOR VANCOR ✅ 6.599 mcg/mL 20.04% 1.26 0.9949

Reference Ranges

Name
Beckman
Roche
Acetaminophen (Tylenol)
Name: Acetaminophen (Tylenol)
Mnemonic: TYL
Units: mcg/mL
Method Code: HAUTO
Female Male
AgeRange AgeRange
0- 0-25 0- 0-25
Effective date: 08/31/2026
Name: Acetaminophen (Tylenol)
Mnemonic: TYL
Units: mcg/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 10-30 0- 10-30
Effective date: 09/14/2026
Alcohol (Ethyl)
Name: Alcohol (Ethyl)
Mnemonic: ETOH
Units: mg/dL
Method Code: HAUTO
Female Male
AgeRange AgeRange
0- Negative [NRN] 0- Negative [NRN]
Effective date: 08/31/2026
Name: Alcohol (Ethyl)
Mnemonic: ETOH
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- Negative [NRN] 0- Negative [NRN]
Effective date: 09/14/2026
Alcohol (Ethyl), URN
Name: Alcohol (Ethyl), URN
Mnemonic: UETOH
Units: mg/dL
Method Code: HAUTO
Female Male
AgeRange AgeRange
0- Negative [NRN] 0- Negative [NRN]
Effective date: 08/31/2026
Name: Alcohol (Ethyl), URN
Mnemonic: UETOH
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- Negative [NRN] 0- Negative [NRN]
Effective date: 09/14/2026
Amikacin, Random Level
Name: Amikacin, Random Level
Mnemonic: AMIKAR
Units: mcg/mL
Method Code: UAUTO
Female Male
AgeRange AgeRange
0- 5.0-30.0 0- 5.0-30.0
Effective date: 08/31/2026
Name: Amikacin, Random Level
Mnemonic: AMIKAR
Units: mcg/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 5.0-30.0 0- 5.0-30.0
Effective date: 09/14/2026
Carbamazepine (Tegretol)
Name: Carbamazepine (Tegretol)
Mnemonic: CBAM
Units: mcg/mL
Method Code: HAUTO
Female Male
AgeRange AgeRange
0- 6.0-12.0 0- 6.0-12.0
Effective date: 08/31/2026
Name: Carbamazepine (Tegretol)
Mnemonic: CBAM
Units: mcg/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 6.0-12.0 0- 6.0-12.0
Effective date: 09/14/2026
Digoxin
Name: Digoxin
Mnemonic: DIG
Units: ng/mL
Method Code: HAUTO
Female Male
AgeRange AgeRange
0- 0.5-1.9 0- 0.5-1.9
Effective date: 08/31/2026
Name: Digoxin
Mnemonic: DIG
Units: ng/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 0.6-1.2 0- 0.6-1.2
Effective date: 09/14/2026
Gentamicin, Random Level
Name: Gentamicin, Random Level
Mnemonic: GENTAR
Units: mcg/mL
Method Code: UAUTO
Female Male
AgeRange AgeRange
0- 0.0-10.0 0- 0.0-10.0
Effective date: 08/31/2026
Name: Gentamicin, Random Level
Mnemonic: GENTAR
Units: mcg/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 0.0-10.0 0- 0.0-10.0
Effective date: 09/14/2026
Lamotrigine
Name: Lamotrigine
Mnemonic: LAMOT
Name: Lamotrigine
Mnemonic: LAMOT
Units: mcg/mL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 2.0-20.0 0- 2.0-20.0
Effective date: 06/20/2016
Levetiracetam
Name: Levetiracetam
Mnemonic: LEVET
Name: Levetiracetam
Mnemonic: LEVET
Units: mcg/mL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 6.0-46.0 0- 6.0-46.0
Effective date: 06/20/2016
Lidocaine
Name: Lidocaine
Mnemonic: LIDO
Units: mcg/mL
Method Code: UAUTO
Female Male
AgeRange AgeRange
0- 1.2-5.0 0- 1.2-5.0
Effective date: 08/31/2026
Name: Lidocaine
Mnemonic: LIDO
Units: mcg/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 1.5-5.0 0- 1.5-5.0
Effective date: 09/14/2026
Lithium
Name: Lithium
Mnemonic: LI
Units: mEq/L
Method Code: HAUTO
Female Male
AgeRange AgeRange
0- 0.50-1.50 0- 0.50-1.50
Effective date: 08/31/2026
Name: Lithium
Mnemonic: LI
Units: mEq/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0.50-1.50 0- 0.50-1.50
Effective date: 09/14/2026
Mycophenolic Acid
Name: Mycophenolic Acid
Mnemonic: MPA
Units: mcg/mL
Method Code: HAUTO
Female Male
AgeRange AgeRange
0- 1.0-3.5 0- 1.0-3.5
Effective date: 08/31/2026
Name: Mycophenolic Acid
Mnemonic: MPA
Units: mcg/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 1-3.5 0- 1-3.5
Effective date: 09/14/2026
Phenobarbital
Name: Phenobarbital
Mnemonic: PHNO
Units: mcg/mL
Method Code: HAUTO
Female Male
AgeRange AgeRange
0- 10.0-30.0 0- 10.0-30.0
Effective date: 08/31/2026
Name: Phenobarbital
Mnemonic: PHNO
Units: mcg/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 10.0-30.0 0- 10.0-30.0
Effective date: 09/14/2026
Phenytoin (Dilantin)
Name: Phenytoin (Dilantin)
Mnemonic: DIL
Units: mcg/mL
Method Code: HAUTO
Female Male
AgeRange AgeRange
0- 10.0-20.0 0- 10.0-20.0
Effective date: 08/31/2026
Name: Phenytoin (Dilantin)
Mnemonic: DIL
Units: mcg/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 10.0-20.0 0- 10.0-20.0
Effective date: 09/14/2026
Salicylate
Name: Salicylate
Mnemonic: ASA
Units: mg/dL
Method Code: HAUTO
Female Male
AgeRange AgeRange
0- 0-30 0- 0-30
Effective date: 08/31/2026
Name: Salicylate
Mnemonic: ASA
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 0-30 0- 0-30
Effective date: 09/14/2026
Theophylline
Name: Theophylline
Mnemonic: THEO
Units: mcg/mL
Method Code: HAUTO
Female Male
AgeRange AgeRange
0- 10.0-20.0 0- 10.0-20.0
Effective date: 08/31/2026
Name: Theophylline
Mnemonic: THEO
Units: mcg/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 10.0-20.0 0- 10.0-20.0
Effective date: 09/14/2026
Tobramycin, Random Level
Name: Tobramycin, Random Level
Mnemonic: TOBRAR
Units: mcg/mL
Method Code: UAUTO
Female Male
AgeRange AgeRange
0- 0.0-10.0 0- 0.0-10.0
Effective date: 08/31/2026
Name: Tobramycin, Random Level
Mnemonic: TOBRAR
Units: mcg/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 0.0-10.0 0- 0.0-10.0
Effective date: 09/14/2026
Valproic Acid (Depakene)
Name: Valproic Acid (Depakene)
Mnemonic: VPA
Units: mcg/mL
Method Code: HAUTO
Female Male
AgeRange AgeRange
0- 50-100 0- 50-100
Effective date: 08/31/2026
Name: Valproic Acid (Depakene)
Mnemonic: VPA
Units: mcg/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 50-100 0- 50-100
Effective date: 09/14/2026
Vancomycin, Random Level
Name: Vancomycin, Random Level
Mnemonic: VANCOR
Units: mcg/mL
Method Code: HAUTO
Female Male
AgeRange AgeRange
0- 5.0-40.0 0- 5.0-40.0
Effective date: 08/31/2026
Name: Vancomycin, Random Level
Mnemonic: VANCOR
Units: mcg/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 5-40 0- 5-40
Effective date: 09/14/2026