Roche Platform Transition

This page compares reference ranges between the Roche and Beckman platforms for the selected category of tests. For a description of the transition from the Beckman to Roche automated chemistry platform, please see the Chemistry and Immunoassay Beckman to Roche Transition Guideline.

All BMP Liver Kidney Misc

Method Comparison

The slope of the linear regression of Roche onto Beckman represents the proportional bias between the two methods (i.e., the proportional change going from Beckman to Roche). The mean bias is expressed as a % or an absolute bias depending on whether there is a proportional bias between Beckman and Roche or a constant bias. A positive mean bias means that Roche results are higher than Beckman results, on average. While it is not recommended to use this information to convert one result directly to the other, the data will help when comparing results across platforms.

Tests with significantly different performance characteristics are reported using different component names and are not trendable in Epic. Certain analytes, labeled "Not comparable," were so poorly correlated that results from Beckman and Roche should not be directly compared for the care of patients. Trends of measurements on the same instrument platform for the same patient over time are interpretable.

Test Name	Beckman Code	Roche Code	Same code/Trendable?	Bias	Percent Bias	Slope of the Linear Regression (Roche vs. Beckman)	Coefficient of Determination (R²)
Albumin	ALB	ALB	✅	-0.12 g/dL	-2.70%	0.92	1.00
Alkaline Phosphatase (Total)	ALK	ALK	✅	4.22 U/L	5.30%	1.03	0.99
ALT (GPT)	ALT	ALTRD	❌	7.35 U/L	38%	1.22	1.00
AST (GOT)	AST	ASTRD	❌	9.75 U/L	36%	1.30	1.00
Bilirubin (Total)	BIL	BILRD	❌	-0.14 mg/dL	-21%	0.89	0.99
Bilirubin (Direct)	BILD	BILDRD	❌	0.10 mg/dL	57.20%	1.11	0.95
Protein (Total)	TP	TPRD	❌	-0.07 g/dL	-1.00%	0.99	1.00

Reference Ranges

Name

Beckman

Roche

Albumin

Name: Albumin
Mnemonic: ALB
Units: g/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	3.5-5.2	0-	3.5-5.2

Effective date: 03/01/2015

Name: Albumin
Mnemonic: ALB
Units: g/dL
Method Code: F3PUR1

Female		Male
Age	Range	Age	Range
0-	3.9-5.2	0-	3.9-5.2

Effective date: 12/23/2025

Alkaline Phosphatase (Total)

Name: Alkaline Phosphatase (Total)
Mnemonic: ALK
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-9y	111-281	0-9y	115-324
10y-11y	132-366	10y-11y	115-324
12y-13y	89-285	12y-13y	119-426
14y-17y	43-226	14y-17y	72-400
18y-24y	26-98	18y-24y	42-136
25y-34y	25-100	25y-34y	35-109
35y-44y	25-112	35y-44y	36-122
45y-54y	34-121	45y-54y	39-139
55y-64y	31-132	55y-64y	37-159
65y-74y	38-172	65y-74y	36-161
75y-199y	49-199	75y-199y	52-227
200y-	36-122	200y-	36-122

Effective date: 04/02/2015

Name: Alkaline Phosphatase (Total)
Mnemonic: ALK
Units: U/L
Method Code: F3PUR1

Female		Male
Age	Range	Age	Range
0-	35-104	0-	40-129

Effective date: 12/23/2025

ALT (GPT)

Name: ALT (Beckman)
Mnemonic: ALT
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	7-33	0-49y	10-64
		50y-	10-48

Effective date: 03/01/2015

Name: ALT (Roche)
Mnemonic: ALTRD
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0-43	0-	0-63

Effective date: 12/12/2025

AST (GOT)

Name: AST (Beckman)
Mnemonic: AST
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	9-38	0-	9-38

Effective date: 03/01/2015

Name: AST (Roche)
Mnemonic: ASTRD
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0-35	0-	0-50

Effective date: 01/12/2026

Bilirubin (Total)

Name: Total Bilirubin (Beckman)
Mnemonic: BIL
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-29d	0.2-1.3	0-29d	0.2-1.3
1m-	0.2-1.3	1m-	0.2-1.3

Effective date: 03/01/2015

Name: Total Bilirubin (Roche)
Mnemonic: BILRD
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-29d	0.0-0.9	0-29d	0.0-0.9
1m-	0.0-1.1	1m-	0.0-1.1

Effective date: 12/17/2025

Bilirubin (Direct)

Name: Direct Bilirubin (Beckman)
Mnemonic: BILD
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0.0-0.3	0-	0.0-0.3

Effective date: 03/01/2015

Name: Direct Bilirubin (Roche)
Mnemonic: BILDRD
Units: mg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0.0-0.4	0-	0.0-0.4

Effective date: 01/12/2026

Protein (Total)

Name: Total Protein (Beckman)
Mnemonic: TP
Units: g/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	6.0-8.2	0-	6.0-8.2

Effective date: 03/01/2015

Name: Total Protein (Roche)
Mnemonic: TPRD
Units: g/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	6.4-8.3	0-	6.4-8.3

Effective date: 01/12/2026

Ammonia

Name: Ammonia, PLASMA (Beckman)
Mnemonic: PLNH3
Units: mcg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
1d-13d	110-180	1d-13d	110-180
14d-29d	95-155	14d-29d	95-155
1m-11y	35-85	1m-11y	35-85
12y-	0-65	12y-	0-65

Effective date: 03/01/2015

Name: Ammonia, Plasma (Roche)
Mnemonic: PNH3RD
Units: mcg/dL
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0-64	0-	0-64

Effective date: 04/19/2026

Gamma Glutamyl Transferase

Name: Gamma Glutamyl Transferase
Mnemonic: GGT
Units: U/L
Method Code: default

Female		Male
Age	Range	Age	Range
0-	0-55	0-	0-55

Effective date: 03/01/2015

Name: Gamma Glutamyl Transferase
Mnemonic: GGT
Units: U/L
Method Code: FMPRO1

Female		Male
Age	Range	Age	Range
0-	<51	0-	<60

Effective date: 03/12/2026