Roche Platform Transition

This page compares reference ranges between the Roche and Beckman platforms for the selected category of tests. For a description of the transition from the Bechman to Roche automated chemistry platform, please see the Roche Transition guideline.

Method Comparison

The slope of the linear regression of Roche onto Beckman represents the proportional bias between the two methods (i.e., the proportional change going from Beckman to Roche). The mean bias is expressed as a % or an absolute bias depending on whether there is a proportional bias between Beckman and Roche or a constant bias. A positive mean bias means that Roche results are higher than Beckman results, on average. While it is not recommended to use this information to convert one result directly to the other, the data will help when comparing results across platforms.

Tests with significantly different performance characteristics are reported using different component names and are not trendable in Epic.

Test Name Beckman Code Roche Code Same code/Trendable? Mean Bias Slope of the Linear Regression (Roche vs. Beckman) Coefficient of Determination (R2)
Albumin ALB ALB -2.7% 0.92 1.00
Alkaline Phosphatase (Total) ALK ALK 5.3% 1.03 0.99
ALT (GPT) ALT ALTRD 38% 1.22 1.00
AST (GOT) AST ASTRD 36% 1.30 1.00
Bilirubin (Total) BIL BILRD -21% 0.89 0.99
Bilirubin (Direct) BILD BILDRD 0.1 mg/dL 1.11 0.95
Protein (Total) TP TPRD -1.0% 0.99 1.00

Reference Ranges

Name
Beckman
Roche
Albumin
Name: Albumin
Mnemonic: ALB
Units: g/dL
Method Code: default
Female Male Unknown
AgeRange AgeRange AgeRange
0- 3.5-5.2 0- 3.5-5.2 0- 3.5-5.2
Effective date: 03/01/2015
Name: Albumin
Mnemonic: ALB
Units: g/dL
Method Code: PENPU1
Female Male Unknown
AgeRange AgeRange AgeRange
0- 3.9-5.2 0- 3.9-5.2
Effective date: 12/10/2025
Alkaline Phosphatase (Total)
Name: Alkaline Phosphatase (Total)
Mnemonic: ALK
Units: U/L
Method Code: default
Female Male Unknown
AgeRange AgeRange AgeRange
0-9y 111-281 0-9y 115-324
10y-11y 132-366 10y-11y 115-324
12y-13y 89-285 12y-13y 119-426
14y-17y 43-226 14y-17y 72-400
18y-24y 26-98 18y-24y 42-136
25y-34y 25-100 25y-34y 35-109
35y-44y 25-112 35y-44y 36-122
45y-54y 34-121 45y-54y 39-139
55y-64y 31-132 55y-64y 37-159
65y-74y 38-172 65y-74y 36-161
75y-199y 49-199 75y-199y 52-227
200y- 36-122 200y- 36-122
Effective date: 04/02/2015
Name: Alkaline Phosphatase (Total)
Mnemonic: ALK
Units: U/L
Method Code: PENPU1
Female Male Unknown
AgeRange AgeRange AgeRange
0- 35-104 0- 40-129 0- 40-104
Effective date: 12/16/2025
ALT (GPT)
Name: ALT (GPT)
Mnemonic: ALT
Units: U/L
Method Code: default
Female Male Unknown
AgeRange AgeRange AgeRange
0- 7-33 0-49y 10-64
50y- 10-48
Effective date: 03/01/2015
Name: ALT (Roche)
Mnemonic: ALTRD
Units: U/L
Method Code: default
Female Male Unknown
AgeRange AgeRange AgeRange
0- 0-43 0- 0-63 0- 0-43
Effective date: 12/12/2025
AST (GOT)
Name: AST (GOT)
Mnemonic: AST
Units: U/L
Method Code: default
Female Male Unknown
AgeRange AgeRange AgeRange
0- 9-38 0- 9-38 0- 9-38
Effective date: 03/01/2015
Name: AST (Roche)
Mnemonic: ASTRD
Units: U/L
Method Code: default
Female Male Unknown
AgeRange AgeRange AgeRange
0- 0-35 0- 0-50 0- 0-35
Effective date: 01/12/2026
Bilirubin (Total)
Name: Bilirubin (Total)
Mnemonic: BIL
Units: mg/dL
Method Code: default
Female Male Unknown
AgeRange AgeRange AgeRange
0-29d 0.2-1.3 0-29d 0.2-1.3 0-29d 0.2-1.3
1m- 0.2-1.3 1m- 0.2-1.3 1m- 0.2-1.3
Effective date: 03/01/2015
Name: Total Bilirubin (Roche)
Mnemonic: BILRD
Units: mg/dL
Method Code: default
Female Male Unknown
AgeRange AgeRange AgeRange
0-29d 0.0-0.9 0-29d 0.0-0.9 0-29d 0.0-0.9
1m- 0.0-1.1 1m- 0.0-1.1 1m- 0.0-1.1
Effective date: 12/17/2025
Bilirubin (Direct)
Name: Bilirubin (Direct)
Mnemonic: BILD
Units: mg/dL
Method Code: default
Female Male Unknown
AgeRange AgeRange AgeRange
0- 0.0-0.3 0- 0.0-0.3 0- 0.0-0.3
Effective date: 03/01/2015
Name: Direct Bilirubin (Roche)
Mnemonic: BILDRD
Units: mg/dL
Method Code: default
Female Male Unknown
AgeRange AgeRange AgeRange
0- 0.0-0.4 0- 0.0-0.4 0- 0.0-0.4
Effective date: 01/12/2026
Protein (Total)
Name: Protein (Total)
Mnemonic: TP
Units: g/dL
Method Code: default
Female Male Unknown
AgeRange AgeRange AgeRange
0- 6.0-8.2 0- 6.0-8.2 0- 6.0-8.2
Effective date: 03/01/2015
Name: Total Protein (Roche)
Mnemonic: TPRD
Units: g/dL
Method Code: default
Female Male Unknown
AgeRange AgeRange AgeRange
0- 6.4-8.3 0- 6.4-8.3 0- 6.4-8.3
Effective date: 01/12/2026