Porphobilinogen Qnt, Rand URN

General Information

Lab Name

Lab Code

UPBGRG

Epic Ordering

Porphobilinogen, Random Urine

Description

STAT requests require approval from Lab Med Resident. Increased urinary porphobilinogen concentration in the presence of acute clinical symptoms is consistent with a biochemical diagnosis of acute porphyria, variegate porphyria, or hereditary coproporphyria. Normal concentrations may be seen in porphyria patients who are asymptomatic at the time of collection.

Synonyms

porphyria, spot urine

Components

Code	Name
UPBGR	Porphobilinogen Qnt, Rand URN
UPBGRM	Porphobilin Qnt, Rand URN Method

Interpretation

Method: Modified Mauzerall-Granick method
Reference Range: See individual components
Ref. Range Notes: The literature reference for this reference range is: Deacon AC, Elder GH. Front line tests for the investigation of suspected porphyria. J Clin Pathol 2001; 54:500-507.

Ordering & Collection

Specimen Type: Urine
Collection: RANDOM URINE: STAT specimens do not need preservative if delivered immediately to the laboratory.

RANDOM URINE: To ROUTINE specimens add approximately 5 g sodium bicarbonate for 30 mL or more urine (1 well rounded tsp). For urine samples less than 30 mL, add sodium bicarbonate to the minimum ratio of 2 mg per mL of urine. HMC Chemistry will provide aliquot tubes containing 200 mg sodium bicarbinate for about 10 mL of urine.

Mix well. Refrigerate in a dark bottle.

For 24-hour urine, see Porphobilinogen Quantitative, 24-h urine (UPBG)
Handling Instructions
Quantity: requested: 50 mL urine
minimum: 10 mL urine

Processing

Processing: Mix well. Refrigerate in a dark bottle.

Performance

LIS Dept Code: Chemistry, Harborview (CHH)
Performing Location(s)
Frequency: Monday to Friday, samples received in Special Chemistry by 11AM. Weekends and holidays, approved STAT only.
Available STAT?: with approval

Billing & Coding

CPT codes: 84110
LOINC: 27382-1
Interfaced Order Code: UOW3503