Porphobilinogen Quantitative, 24-h urine

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General Information

Lab Name
Porphobilinogen Quant, URN
Lab Code
UPBG
Epic Ordering
Porphobilinogen, 24 hr Urine
Description

Porphobilinogen is enriched by ion exchange chromatography and detected spectrophotometrically following its reaction with Ehrlich's reagent. The reportable range is 0 to 528 mg/L with imprecision 6.8% CV.

Increased urinary porphobilinogen excretion with a history of suggestive clinical symptoms is consistent with a biochemical diagnosis of acute porphyria, variegate porphyria, or hereditary coproporphyria. Porphyria Foundation Website

Synonyms
Porphyria
Components

Interpretation

Method

Modified Mauzerall-Granick method

Reference Range
See individual components

Ordering & Collection

Specimen Type
Urine
Collection

24 HOUR URINE collected in dark bottle with 5 g Sodium Bicarbonate

For random urine, see Porphobilinogen Quantitative, Random urine [UPBGR]

Handling Instructions

Note: If patient @ home, can add 2-3 tsp Baking Soda to container and keep in paper bag to protect from light.

Quantity
requested: 50 mL urine
minimum: 10 mL urine

Processing

Processing

Mix, measure and record Total Volume. Refrigerate in dark bottle. Note: If this test is ordered along with Urine Porphyrin, see RUPORG.

Performance

LIS Dept Code
Chemistry, Harborview (CHH)
Performing Location(s)
HMC Chemistry, Special
206-520-4600

325 9th Ave, Rm # GWH-47, Seattle, WA 98104-2420

Frequency
Tuesday
Available STAT?
No

Billing & Coding

CPT codes
84110
LOINC
27382-1
Interfaced Order Code
UOW573