Chikungunya Virus IgG and IgM Antibodies (Sendout)

General Information

Lab Name

Lab Code

RCHIKV

Epic Name

Chikungunya Virus IgG and IgM Antibodies (Sendout)

External Test Id

2011812

Description

Ordering Recommendation: May aid in the diagnosis of chikungunya viral infection during acute phase of disease (>5 days after symptom onset). Testing should also be considered for other arthropod-borne viruses with similar symptomology based on clinical presentation and travel history.

Collection Note: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Specimens must be plainly marked as "acute" or "convalescent."

References

ARUP Consult Topic: Dengue, West Nile, and Other Mosquito-Borne Arboviruses
WA State Department of Health: Arboviral Disease

Synonyms

2011812, Arbovirus, CHIKPAN, Chikungunya, CHIKV

Components

Code	Name
RCHIKG	Chikungunya Virus IgG Antibody
RCHIKM	Chikungunya Virus IgM Antibody

Interpretation

Guidelines

Washington DOH Notifiable Conditions

Method

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reference Range

See individual components

Ref. Range Notes

Chikungunya Antibody, IgG:

Index:	Interpretation:
0.79 IV or less	Negative: No significant level of Chikungunya IgG antibody detected.
0.80-1.09 IV	Equivocal: Questionable presence of Chikungunya IgG antibody detected. Repeat testing in 10-14 days may be helpful.
1.10 IV or greater	Positive: Chikungunya IgG antibody detected; suggests current or past infection.

Chikungunya Antibody, IgM:

Index:	Interpretation:
0.79 IV or less	Negative: No significant level of Chikungunya IgM antibody detected.
0.80-1.09 IV	Equivocal: Questionable presence of Chikungunya IgM antibody detected. Repeat testing in 10-14 days may be helpful.
1.10 IV or greater	Positive: Chikungunya IgM antibody detected.

References

ARUP Consult Topic: Dengue, West Nile, and Other Mosquito-Borne Arboviruses
WA State Department of Health: Arboviral Disease

Ordering & Collection

Specimen Type: Blood
Collection: 3 mL blood in GOLD SST or RED TOP tube

Also Accepted: Green top (Heparin) or Lavender top (EDTA) tube
Handling Instructions: Outside Laboratories: Centrifuge sample and transfer serum/plasma to a separate plastic vial within 2 hours of collection. Refrigerate serum/plasma.

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year; Ambient: 48 hours. Avoid repeated freeze/thaw cycles.

Unacceptable Conditions: Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
Quantity: Requested: 1 mL serum or plasma
Minimum: 0.15 mL serum or plasma

Processing

Receiving Instructions

Centrifuge sample and transfer serum/plasma to a separate plastic vial within 2 hours of collection. Refrigerate serum/plasma.

Sendouts:

Order ARUP Test: 2011812
Interfaced: Yes [Interface: 602; Department: ARPR]
If parallel testing will be performed:
- Mark serum samples as "acute" or "convalescent," as appropriate. Convalescent samples must be received by ARUP within 30 days from receipt of the acute sample.
- On the Sunquest-generated batch sheet, indicate "run parallel testing with acute sample collected (MM/DD/YY)" next to the associated order.

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year; Ambient: 48 hours. Avoid repeated freeze/thaw cycles.

Unacceptable Conditions: Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.

Misc Sendout

Performance

Lab Department

Sendouts ARUP Lab (RF)(ARPR)

Frequency

Setup Wednesday. Results in 1-8 days.

Available STAT?

Performing Location(s)

Sendout	ARUP Laboratories, Inc. 800-522-2787 500 Chipeta Way Salt Lake City, UT 84108

Billing & Coding

CPT Codes: 86790x2
LOINC: 43064-5