Serologic Syphilis Screen

General Information

Lab Name
Serologic Syphilis Screen
Lab Code
SYPHSC
Epic Name
Syphilis Screen
Description

Samples that are screened at borderline/reactive will be sent to the state lab for supplemental testing.

To diagnose congenital syphilis in neonate/infants and to monitor treatment responses, quantitative RPR testing should be performed instead of the serologic syphilis screen. For congenital syphilis diagnosis, concurrent quantitative RPR testing of maternal serum should be obtained, to enable comparison between neonatal and maternal RPR titers.

Synonyms
reagin, RPR, SYPHS, Treponema pallidum
Components

Interpretation

Guidelines
Method

Multiplex immunoassay

Reference Range
See individual components

Ordering & Collection

Specimen Type
Serum
Collection

Preferred: 6 mL blood in GOLD SST Tube

Also Acceptable: RED TOP

Plasma can only be used if a serum sample is not available and the use of plasma has been approved by the Lab Medicine Resident. Note: if screening results are not negative, a serum sample will need to be drawn for the mandatory State Lab supplemental testing, leading to reporting delays.

Unacceptable: Green, Lavender, Orange RST or Blue Top tube.

Handling Instructions

Stability: Refrigerated: 14 days (preferred); Frozen at -20°C or colder: Long Term (avoid repeated freeze-thaws)

Quantity
Requested: 2 mL serum
Minimum: 1.2 mL serum

Processing

Receiving Instructions

Refrigerate serum

STAT requests need approval from Lab Medicine Resident on call

Misc Sendout

Performance

Lab Department
Immunology(IMM)
Frequency
Monday-Friday
Available STAT?
No
Performing Location(s)
UW-MT Immunology
206-520-4600

Clinical Lab, Room NW220,
University of Washington Medical Center,
1959 NE Pacific street, Seattle, WA 98195

Billing & Coding

CPT Codes
86780
LOINC
34954-8
Interfaced Order Code
UOW3611