Serologic Syphilis Screen
General Information
- Lab Name
 - Serologic Syphilis Screen
 - Lab Code
 - SYPHSC
 - Epic Name
 - Syphilis Screen
 - Description
 Samples that are screened at borderline/reactive will be sent to the state lab for supplemental testing.
To diagnose congenital syphilis in neonate/infants and to monitor treatment responses, quantitative RPR testing should be performed instead of the serologic syphilis screen. For congenital syphilis diagnosis, concurrent quantitative RPR testing of maternal serum should be obtained, to enable comparison between neonatal and maternal RPR titers.
- Synonyms
 - reagin, RPR, SYPHS, Treponema pallidum
 - Components
 - 
    
  
    
Code Name SYPHT T. pallidum IgG/IgM Ab (Bioplex) RPRSCB RPR Screen SYPHSI Syphilis Screening Status  
Interpretation
- Guidelines
 - Method
 Multiplex immunoassay
- Reference Range
 - See individual components
 
Ordering & Collection
- Specimen Type
 - Serum
 - Collection
 - 
    
    
Preferred: 6 mL blood in GOLD SST Tube
Also Acceptable: RED TOP
Plasma can only be used if a serum sample is not available and the use of plasma has been approved by the Lab Medicine Resident. Note: if screening results are not negative, a serum sample will need to be drawn for the mandatory State Lab supplemental testing, leading to reporting delays.
Unacceptable: Green, Lavender, Orange RST or Blue Top tube.
 - Handling Instructions
 Stability: Refrigerated: 14 days (preferred); Frozen at -20°C or colder: Long Term (avoid repeated freeze-thaws)
- Quantity
 - 
    
      Requested: 2 mL serum
      
Minimum: 1.2 mL serum 
Processing
- Receiving Instructions
 Refrigerate serum
STAT requests need approval from Lab Medicine Resident on call
- Misc Sendout
 
Performance
- Lab Department
 - Immunology(IMM)
 - Frequency
 - Monday-Friday
 - Available STAT?
 - No
 - Performing Location(s)
 - 
    
      
UW-MT Immunology 
206-520-4600Clinical Lab, Room NW220,
University of Washington Medical Center,
1959 NE Pacific street, Seattle, WA 98195 
Billing & Coding
- CPT Codes
 - 86780
 - LOINC
 - 34954-8
 - Interfaced Order Code
 - UOW3611