Trypanosoma cruzi IgG Antibody (Sendout)

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General Information

Lab Name
Trypanosoma cruzi IgG Antibody (Sendout)
Lab Code
RTRYPG
Epic Name
Trypanosoma cruzi IgG Antibody (Sendout)
External Test Id
0051076
Description

Useful For: Aiding in the diagnosis of non-acute (chronic phase) Chagas disease (T. cruzi).

Ordering Guidance: Secondary serologic test for the diagnosis of Trypanosoma cruzi infection. The preferred initial test is RCHAGS (Trypanosoma cruzi Total Antibody, Sendout) to Mayo Clinic Laboratories. The CDC recommends performing 2 independent tests for the serologic diagnosis of Chagas disease¹.

References
  1. Centers for Disease Control and Prevention (CDC): Laboratory Diagnosis of American Trypanosomiasis
Synonyms
0051076, American trypanosomiasis, Chagas Antibody IgG, Chagas Disease, T. cruzi, Tcruzi IgG Ab, Trypanosomiasis
Components
Code Name
RTRYPR Trypanosoma cruzi IgG Antibody

Interpretation

Guidelines
Method

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reference Range
See individual components
Ref. Range Notes

Reference Interval: <=1.0 IV

Interpretation:

<=1.0 IV:

Negative - No significant level of Trypanosoma cruzi IgG antibody detected.
1.1 IV:

Equivocal - Questionable presence of Trypanosoma cruzi IgG antibody detected. Repeat testing in 10-14 days may be helpful.
>=1.2 IV: Positive - IgG antibodies to Trypanosoma cruzi detected, which may suggest current or past infection.
Interferences and Limitations

Cautions: This assay should not be used for blood donor screening or associated re-entry protocols, or for screening Human Cell and Cellular Tissue-Based Products (HCT/Ps). According to the CDC, at least two different serologic tests should be used to make the laboratory diagnosis of chronic Chagas Disease, as no single serologic test is sufficiently sensitive and specific.

References
  1. Centers for Disease Control and Prevention (CDC): Laboratory Diagnosis of American Trypanosomiasis

Ordering & Collection

Specimen Type
Blood
Collection

3 mL blood in GOLD TOP SST or RED TOP tube

Handling Instructions

Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

Stability: Frozen: 1 year; Refrigerated: 2 weeks; Ambient: 48 hours.

Unacceptable Conditions: Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

Quantity
Requested: 0.5 mL serum
Minimum: 0.3 mL serum

Processing

Receiving Instructions

Centrifuge sample and transfer serum to a separate plastic vial within two hours of collection. Refrigerate serum.

Sendouts:

  • Order ARUP Test: 0051076.
  • Interfaced: Yes. [Interface Number: 602; Department: ARPR]

Stability: Frozen: 1 year; Refrigerated: 2 weeks; Ambient: 48 hours.

Unacceptable Conditions: Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

Misc Sendout

Performance

Lab Department
Sendouts ARUP Lab (RF)(ARPR)
Frequency
Performed: Wednesday. Reported: 1-8 days.
Available STAT?
No
Performing Location(s)
Sendout ARUP Laboratories, Inc.
800-522-2787

500 Chipeta Way
Salt Lake City, UT 84108

Billing & Coding

CPT Codes
86753
LOINC
59387-1