Useful For: Aiding in the diagnosis of non-acute (chronic phase) Chagas disease (T. cruzi).
Ordering Guidance: Secondary serologic test for the diagnosis of Trypanosoma cruzi infection. The preferred initial test is RCHAGS (Trypanosoma cruzi Total Antibody, Sendout) to Mayo Clinic Laboratories. The CDC recommends performing 2 independent tests for the serologic diagnosis of Chagas diseaseĀ¹.
Code | Name |
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RTRYPR | Trypanosoma cruzi IgG Antibody |
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Reference Interval: <=1.0 IV
Interpretation:
<=1.0 IV: |
Negative - No significant level of Trypanosoma cruzi IgG antibody detected. |
1.1 IV: |
Equivocal - Questionable presence of Trypanosoma cruzi IgG antibody detected. Repeat testing in 10-14 days may be helpful. |
>=1.2 IV: | Positive - IgG antibodies to Trypanosoma cruzi detected, which may suggest current or past infection. |
Cautions: This assay should not be used for blood donor screening or associated re-entry protocols, or for screening Human Cell and Cellular Tissue-Based Products (HCT/Ps). According to the CDC, at least two different serologic tests should be used to make the laboratory diagnosis of chronic Chagas Disease, as no single serologic test is sufficiently sensitive and specific.
3 mL blood in GOLD TOP SST or RED TOP tube
Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.
Stability: Frozen: 1 year; Refrigerated: 2 weeks; Ambient: 48 hours.
Unacceptable Conditions: Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
Centrifuge sample and transfer serum to a separate plastic vial within two hours of collection. Refrigerate serum.
Sendouts:
Stability: Frozen: 1 year; Refrigerated: 2 weeks; Ambient: 48 hours.
Unacceptable Conditions: Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
Sendout |
ARUP Laboratories, Inc.
800-522-2787 500 Chipeta Way |
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