Trypanosoma cruzi IgG Antibody (Sendout)
General Information
- Lab Name
- Trypanosoma cruzi IgG Antibody (Sendout)
- Lab Code
- RTRYPG
- Epic Ordering
- Trypanosoma cruzi IgG Antibody (Sendout)
- External Test Id
- 0051076
- Description
Useful For: Aiding in the diagnosis of non-acute (chronic phase) Chagas disease (T. cruzi).
Ordering Guidance: Secondary serologic test for the diagnosis of Trypanosoma cruzi infection. The preferred initial test is RCHAGS (Trypanosoma cruzi Total Antibody, Sendout) to Mayo Clinic Laboratories. The CDC recommends performing 2 independent tests for the serologic diagnosis of Chagas disease¹.
- References
- Centers for Disease Control and Prevention (CDC): Laboratory Diagnosis of American Trypanosomiasis
- Synonyms
- 0051076, American trypanosomiasis, Chagas Antibody IgG, Chagas Disease, T. cruzi, Tcruzi IgG Ab, Trypanosomiasis
- Components
-
Code Name RTRYPR Trypanosoma cruzi IgG Antibody
Interpretation
- Method
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
- Reference Range
- See individual components
- Ref. Range Notes
Reference Interval: <=1.0 IV
Interpretation:
<=1.0 IV: Negative - No significant level of Trypanosoma cruzi IgG antibody detected.
1.1 IV: Equivocal - Questionable presence of Trypanosoma cruzi IgG antibody detected. Repeat testing in 10-14 days may be helpful.
>=1.2 IV: Positive - IgG antibodies to Trypanosoma cruzi detected, which may suggest current or past infection. - Interferences and Limitations
Cautions: This assay should not be used for blood donor screening or associated re-entry protocols, or for screening Human Cell and Cellular Tissue-Based Products (HCT/Ps). According to the CDC, at least two different serologic tests should be used to make the laboratory diagnosis of chronic Chagas Disease, as no single serologic test is sufficiently sensitive and specific.
- References
- Centers for Disease Control and Prevention (CDC): Laboratory Diagnosis of American Trypanosomiasis
- Guidelines
Ordering & Collection
- Specimen Type
- Blood
- Collection
-
3 mL blood in GOLD TOP SST or RED TOP tube
- Handling Instructions
Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.
Stability: Frozen: 1 year; Refrigerated: 2 weeks; Ambient: 48 hours.
Unacceptable Conditions: Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
- Quantity
-
requested: 0.5 mL serum
minimum: 0.3 mL serum
Processing
- Processing
Centrifuge sample and transfer serum to a separate plastic vial within two hours of collection. Refrigerate serum.
Sendouts:
- Order ARUP Test: 0051076.
- Interfaced: Yes. [Interface Number: 602; Department: ARPR]
Stability: Frozen: 1 year; Refrigerated: 2 weeks; Ambient: 48 hours.
Unacceptable Conditions: Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
Performance
- LIS Dept Code
- Sendouts ARUP Lab (RF) (ARPR)
- Performing Location(s)
-
Sendout ARUP Laboratories, Inc.
800-522-2787500 Chipeta Way
Salt Lake City, UT 84108 - Frequency
- Performed: Wednesday. Reported: 1-8 days.
- Available STAT?
- No
Billing & Coding
- CPT codes
- 86753
- LOINC
- 59387-1