Q Fever Antibody Screen, Reflex to Titer (Sendout)
General Information
- Lab Name
- Q Fever Antibody Screen, Reflex to Titer (Sendout)
- Lab Code
- RQFVRS
- Epic Name
- Q Fever Antibody Screen, Reflex to Titer (Sendout)
- External Test Id
- QFEVR
- Description
Useful For: Screening for exposure to Coxiella burnetii, the causative agent of Q fever. This test should not be used as a screening procedure for the general population.
Testing Algorithm: If the Q fever serology result is reactive, then Q Fever IgG and IgM Antibodies (Sendout) [RQFP] by indirect immunofluorescence will be performed at an additional charge.
- Synonyms
- Coxiella burnetii, Febrile Agglutinins, OS-K (Proteus OX-K - Weil-Felix), OX-19 (Proteus OX-19 - Weil-Felix), OX-2 (Proteus OX-2 - Weil-Felix), Proteus (Weil-Felix), Q-Fever, QFEVER, QFEVR, QFP, Rickettsial Antibody, Typhus, Weil-Felix
- Components
-
Code Name RQFVRR Q Fever Antibody Screen
Interpretation
- Guidelines
- Method
Enzyme-Linked Immunosorbent Assay (ELISA)
- Reference Range
- See individual components
- Ref. Range Notes
Interpretation:
Negative: No antibodies to Q fever (Coxiella burnetii) detected. Repeat testing on a new sample collected in 2 to 3 weeks if acute Q fever is suspected.
Reactive: Not diagnostic. Sample reflexed to the indirect immunofluorescence assay to determine Q fever (Coxiella burnetii) phase I and phase II IgM and IgG titers.
- Interferences and Limitations
Cautions: Serologic responses are time dependent. Specimens collected too early in the disease may not have detectable antibody levels. A second specimen collected 2 to 3 weeks may be necessary to detect antibody.
Cross-reactivity may occur with other closely related intracellular organisms (e.g., Rickettsia spp).
Ordering & Collection
- Specimen Type
- Blood
- Collection
-
3 mL in GOLD SST or RED TOP tube
- Handling Instructions
Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.
Stability: Refrigerated (preferred): 7 days; Frozen: 7 Days; Ambient: Unacceptable.
Reject Due To: Gross hemolysis, gross lipemia, gross icterus, heat-inactivated specimen.
- Quantity
-
Requested: 0.6 mL serum
Minimum: 0.5 mL serum
Processing
- Receiving Instructions
Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.
Sendouts:
- Order Mayo Test: QFEVR.
- Interfaced: Yes.
Stability: Refrigerated (preferred): 7 days; Frozen: 7 Days; Ambient: Unacceptable.
Reject Due To: Gross hemolysis, gross lipemia, gross icterus, heat-inactivated specimen.
- Misc Sendout
Performance
- Lab Department
- Sendouts Mayo Lab (RF)(MARF)
- Frequency
- Performed: Sunday - Friday. Report Available: 1-4 days from sample receipt.
- Available STAT?
- No
- Performing Location(s)
-
Sendout Mayo Clinic Laboratories (Superior Drive)
800-533-17103050 Superior Drive NW
Rochester, MN 55901
Billing & Coding
- CPT Codes
- 86638
- LOINC
- 23019-3
- Interfaced Order Code
- UOW4834