Prenatal Integrated Screen, 2nd Trimester (Sendout)
General Information
- Lab Name
- Prenatal Integrated Screen, 2nd Trimester (Sendout)
- Lab Code
- RINTP2
- Epic Name
- Prenatal Integrated Screen, 2nd Trimester (Sendout)
- External Test Id
- 3000149
- Description
Ordering Recommendation: Second-trimester screening test for trisomy 21 (Down syndrome), trisomy 18 (Edwards), and open neural tube defects. Requires a previously submitted first-trimester specimen, Prenatal Integrated Screen, 1st Trimester (Sendout) [RINTP1]. Risks are determined after second-trimester specimen is received, using a combination of first- and second-trimester serum markers with or without first-trimester nuchal translucency measurement.
Patient Preparation: Specimen must be drawn between 14 weeks, 0 days and 24 weeks, 6 days gestation. The recommended time for maternal serum screening is 16 to 18 weeks gestation.
Ordering Requirements: Requires that a previous first trimester integrated screening has been performed. The patient information provided with the Prenatal Integrated Screen, 1st Trimester (Sendout) [RINTP1] will be used to calculate the risk.
- References
- Synonyms
- 3000149, Maternal Serum Integrated Screen, PRINT2, RSEQM2, Second Trimester Screening, Trisomy
- Components
-
Code Name RPSAFP AFP RMOMFP MoM for AFP RPUE3 uE3 RPMUE3 MoM for uE3 RPHCG2 hCG, 2nd Trimester RHCGM2 hCG MoM, 2nd Trimester RPTDIA Dimeric Inhibin A (DIA) RMODIA MoM for DIA RPAPPA PAPP A Maternal RMOMPA MoM for PAPP A RPNUCT Nuchal Translucency (NT) RMOMNT MoM for NT RPNUCB Nuchal Translucency (NT), Twin B RMOMNB MoM for NT, Twin B RPINTP Maternal Screen Interpretation RPAGED Patient Age at Delivery RPMWGT Patient Weight RPSEDD Estimated Due Date RPGST2 Gestational Age for Second Specimen RPDATM Dating Method RPNFET Number of Fetuses RPINSD Insulin Dependent Diabetes RPSMOK Smoker RHXNTD Family History of Neural Tube Defect RPFHXA Family History of Aneuploidy RPSPEC Initial or Repeat Specimen RPCRLA Crown Rump Length RPCRLB Crown Rump Length, Twin B RPSONC Sonographer Certification Number RPSONN Sonographer Name RPUSDT Ultrasound Date RPIN2L Prenatal Integrated Screen, 2nd Trimester Performing Lab
Interpretation
- Method
Quantitative Chemiluminescent Immunoassay
- Reference Range
- See individual components
- Ref. Range Notes
Refer to report.
Ordering & Collection
- Specimen Type
- Blood
- Collection
-
9 mL blood in GOLD SST or RED TOP tube
- Forms & Requisitions
- UW Medicine DLMP General Requisition
- Use client-specific requisition when available. To obtain a client-specific requisition, contact Client Support Services via email at: commserv@uw.edu.
- UW Medicine DLMP General Requisition
- Handling Instructions
Outside Laboratories:
- Centrifuge sample and transfer 3 mL (1 mL min) serum to a separate plastic vial. Serum must be separated from cells within 2 hours of collection. Refrigerate serum.
- Requires that a Prenatal Integrated Screen, 1st Trimester (Sendout) [RINTP1] has been performed. Submit samples along with a completed DLMP requisition. A separate ARUP requisition is not required; the information from the first integrated screen will be used to perform testing.
Stability (after separation from cells): Refrigerated (preferred): 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles); Ambient: 72 hours.
Unacceptable Conditions: Plasma, hemolyzed specimens.
- Quantity
-
Requested: 3 mL serum
Minimum: 1 mL serum
Processing
- Receiving Instructions
Centrifuge sample and transfer 3 mL (1 mL minimum) serum to a separate plastic vial. Serum must be separated from cells within 2 hours of collection. Refrigerate serum.
Sendouts:
- Order ARUP Test: 3000149.
- Interfaced: Yes. [Interface: 602; Department: ARPR]
Stability (after separation from cells): Refrigerated (preferred): 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles); Ambient: 72 hours.
Unacceptable Conditions: Plasma, hemolyzed specimens.
- Misc Sendout
Performance
- Lab Department
- Sendouts ARUP Lab (RF)(ARPR)
- Frequency
- Performed: Sunday - Saturday. Reported: 2-4 days from sample receipt at ARUP. Missing information may further delay testing.
- Available STAT?
- No
- Performing Location(s)
-
Sendout ARUP Laboratories, Inc.
800-522-2787500 Chipeta Way
Salt Lake City, UT 84108
Billing & Coding
- CPT Codes
- 81511
- LOINC
- 49085-4