Histoplasma Fungal Serology (Sendout)

General Information

Lab Name

Lab Code

RHSTG

Epic Name

Histoplasma Fungal Serology (Sendout)

External Test Id

0050627

Description

Ordering Recommendation: Aids in the diagnosis of histoplasmosis. The immunodiffusion component of this test detects total antibodies against the H and M antigens of Histoplasma capsulatum. The complement fixation component of this test detects total antibodies to mycelial and yeast antigens of Histoplasma.

Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens.

Ordering Note: For testing on CSF samples, refer to Fungal Antibody Panel, CSF (Sendout) [RCFAP].

References

ARUP Laboratories Histoplasma Antibodies by Complement Fixation and Immunodiffusion

Synonyms

0050627, ASP, CF, Complement Fixation, Fungal Antibody, Fungal Serology, Histoplasma, ID, Immunodiffusion, Precipitin

Components

Code	Name
RHISMC	Histoplasma Mycelia by CF
RHISYC	Histoplasma Yeast by CF
RHISID	Histoplasma Antibodies by ID

Interpretation

Guidelines

Washington DOH Notifiable Conditions

Method

Semi-Quantitative Complement Fixation/Immunodiffusion

Reference Range

See individual components

Ref. Range Notes

Reference Intervals:

Histoplasma Antibodies by ID	Not detected
Histoplasma Mycelia Antibodies by CF	<1:8
Histoplasma Yeast Antibodies by CF	<1:8

References

ARUP Laboratories Histoplasma Antibodies by Complement Fixation and Immunodiffusion

Ordering & Collection

Specimen Type: Blood
Collection: 6 mL blood in RED TOP tube or GOLD SST
Handling Instructions: Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles); Ambient: 48 hrs.

Unacceptable Conditions: Contaminated, hemolyzed, or severely lipemic specimens.
Quantity: Requested: 2 mL serum
Minimum: 0.8 mL serum

Processing

Receiving Instructions

Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

Sendouts:

Order ARUP Test: 0050627.
Interfaced: Yes. [Interface Number: 602; Department: ARPR]
If parallel testing will be performed:
- Mark serum samples as "acute" or "convalescent," as appropriate. Convalescent samples must be received by ARUP within 30 days from receipt of the acute sample.
- For the convalescent order, enter instructions in the modifier before batching sample. Comment: Run parallel testing with acute sample collected (MM/DD/YY).

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles); Ambient: 48 hrs.

Unacceptable Conditions: Contaminated, hemolyzed, or severely lipemic specimens.

Misc Sendout

Performance

Lab Department

Sendouts ARUP Lab (RF)(ARPR)

Frequency

Performed: Sunday - Saturday. Reported: 3-6 days.

Available STAT?

Performing Location(s)

Sendout	ARUP Laboratories, Inc. 800-522-2787 500 Chipeta Way Salt Lake City, UT 84108

Billing & Coding

CPT Codes: 86698x3
LOINC: 22347-9
Interfaced Order Code: UOW5074