Histoplasma Fungal Serology (Sendout)

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General Information

Lab Name
Histoplasma Fungal Serology (Sendout)
Lab Code
RHSTG
Epic Ordering
Histoplasma Fungal Serology (Sendout)
External Test Id
0050627
Description

Ordering Recommendation: Aids in the diagnosis of histoplasmosis. The immunodiffusion component of this test detects total antibodies against the H and M antigens of Histoplasma capsulatum. The complement fixation component of this test detects total antibodies to mycelial and yeast antigens of Histoplasma.

Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens.

Ordering Note: For testing on CSF samples, refer to Fungal Antibody Panel, CSF (Sendout) [RCFAP].

References
  1. ARUP Laboratories Histoplasma Antibodies by Complement Fixation and Immunodiffusion
Synonyms
0050627, ASP, CF, Complement Fixation, Fungal Antibody, Fungal Serology, Histoplasma, ID, Immunodiffusion, Precipitin
Components

Interpretation

Method

Semi-Quantitative Complement Fixation/Immunodiffusion

Reference Range
See individual components
Ref. Range Notes

Reference Intervals:

Histoplasma Antibodies by ID Not detected
Histoplasma Mycelia Antibodies by CF <1:8
Histoplasma Yeast Antibodies by CF <1:8
Guidelines

Ordering & Collection

Specimen Type
Blood
Collection

6 mL blood in RED TOP tube or GOLD SST

Handling Instructions

Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles); Ambient: 48 hrs.

Unacceptable Conditions: Contaminated, hemolyzed, or severely lipemic specimens.

Quantity
requested: 2 mL serum
minimum: 0.8 mL serum

Processing

Processing

Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

Sendouts:

  • Order ARUP Test: 0050627.
  • Interfaced: Yes. [Interface Number: 602; Department: ARPR]
  • If parallel testing will be performed:
    • Mark serum samples as "acute" or "convalescent," as appropriate. Convalescent samples must be received by ARUP within 30 days from receipt of the acute sample.
    • For the convalescent order, enter instructions in the modifier before batching sample. Comment: Run parallel testing with acute sample collected (MM/DD/YY).

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles); Ambient: 48 hrs.

Unacceptable Conditions: Contaminated, hemolyzed, or severely lipemic specimens.

Performance

LIS Dept Code
Sendouts ARUP Lab (RF) (ARPR)
Performing Location(s)
Sendout ARUP Laboratories, Inc.
800-522-2787

500 Chipeta Way
Salt Lake City, UT 84108

Frequency
Performed: Sunday - Saturday. Reported: 3-6 days.
Available STAT?
No

Billing & Coding

CPT codes
86698x3
LOINC
22347-9
Interfaced Order Code
UOW5074