LRP4 Autoantibody Test (Sendout)

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General Information

Lab Name
Lab Code
1055
External Test Id
94744
Description

Clinical Significance: Detects anti-LRP4 (low density lipoprotein receptor-related protein 4) in the sera of patients with Myasthenia Gravis (MG). The LRP4 protein activates MuSK kinase activity and promotes the clustering of AChR and their stabilization at the NMJ. Anti-LRP4 antibodies are found in approximately 9.2% (range 2% to 50%) of MG patients who are negative for both anti-AChR and anti-MuSK.

Synonyms
1483, 94744, Anti-LRP4, Low density lipoprotein receptor-related protein 4 antibody, LRP4 Antibody, Myasthenia Gravis
Components

Interpretation

Method

Immunofluorescence Assay (IFA)

Reference Range

Ordering & Collection

Specimen Type
Blood
Collection

6 mL blood in RED TOP tube or GOLD SST

Quantity
Requested: 2 mL serum
Minimum: 0.5 mL serum

Processing

Receiving Instructions

Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.

Login: SEND1-;REFRIG

  • RSNDT1: ATHENA
  • RSTYP1: SRM
  • RTSRQ1: ;LRP4 Autoantibody Test (Quest Test 94744)

Sendouts:

  • Use the QuestQuanum Portal (SJC Account) to order Quest/Athena Test: 94744.
  • Package sample with Quest batch list for courier pickup. (Quest forwards to Athena.)

Stability: Refrigerated (preferred): 25 days; Frozen: 25 days; Ambient: 72 hours.

Misc Sendout

Performance

Lab Department
Frequency
Set up: Varies. Report Available: 7-14 days.
Available STAT?
No
Performing Location(s)
Sendout Athena Diagnostics
800-394-4493

200 Forest St.
2nd Floor
Marlborough, MA 01752

Billing & Coding

Billing Comments

CPT: 86255