LRP4 Autoantibody Test (Sendout)
General Information
- Lab Name
- Lab Code
- 1055
- External Test Id
- 94744
- Description
Clinical Significance: Detects anti-LRP4 (low density lipoprotein receptor-related protein 4) in the sera of patients with Myasthenia Gravis (MG). The LRP4 protein activates MuSK kinase activity and promotes the clustering of AChR and their stabilization at the NMJ. Anti-LRP4 antibodies are found in approximately 9.2% (range 2% to 50%) of MG patients who are negative for both anti-AChR and anti-MuSK.
- Synonyms
- 1483, 94744, Anti-LRP4, Low density lipoprotein receptor-related protein 4 antibody, LRP4 Antibody, Myasthenia Gravis
- Components
Interpretation
- Method
Immunofluorescence Assay (IFA)
- Reference Range
Ordering & Collection
- Specimen Type
- Blood
- Collection
-
6 mL blood in RED TOP tube or GOLD SST
- Quantity
-
Requested: 2 mL serum
Minimum: 0.5 mL serum
Processing
- Receiving Instructions
Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.
Login: SEND1-;REFRIG
- RSNDT1: ATHENA
- RSTYP1: SRM
- RTSRQ1: ;LRP4 Autoantibody Test (Quest Test 94744)
Sendouts:
- Use the QuestQuanum Portal (SJC Account) to order Quest/Athena Test: 94744.
- Package sample with Quest batch list for courier pickup. (Quest forwards to Athena.)
Stability: Refrigerated (preferred): 25 days; Frozen: 25 days; Ambient: 72 hours.
- Misc Sendout
Performance
- Lab Department
- Frequency
- Set up: Varies. Report Available: 7-14 days.
- Available STAT?
- No
- Performing Location(s)
-
Sendout Athena Diagnostics
800-394-4493200 Forest St.
2nd Floor
Marlborough, MA 01752
Billing & Coding
- Billing Comments
CPT: 86255