Cadmium, Urine (Sendout)
General Information
- Lab Name
- Cadmium, URN
- Lab Code
- RUCD
- Epic Ordering
- Cadmium, Urine
- External Test Id
- CDU, CDUCR
- Description
Useful For: Detecting exposure to cadmium, a toxic heavy metal, in urine specimens.
Note: If a random urine specimen is submitted, the Cadmium/Creatinine Ratio, Random Urine test will be performed and results will be reported under Reference Laboratory Test 1 (SEND1).
- Synonyms
- Cd, CDU, CDUCR
- Components
-
Code Name CDINT Cadmium Interval, URN CDTV Cadmium Total Volume, URN RCDT Cadmium,24h, URN
Interpretation
- Method
Triple Quadrupole Inductively Coupled Plasma-Mass Spectrometry (ICP-MS/MS)
- Reference Range
- See individual components
- Ref. Range Notes
Interpretation:
Urine cadmium levels primarily reflect total body burden of cadmium. Cadmium excretion above 3.0 mcg/g creatinine indicates significant exposure to cadmium.
For occupational testing, OSHA cadmium standard is less than 3.0 mcg/g creatinine and the biological exposure index is 5 mcg/g creatinine.
- Interferences and Limitations
Cautions: Collection of urine specimens through a catheter frequently results in elevated values, because rubber contains trace amounts of cadmium that are extracted as urine passes through the catheter.
Ordering & Collection
- Specimen Type
- Urine
- Collection
-
Patient Preparation: High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Collection:
- 24 Hour Urine Collection (Preferred):
- Collect urine for 24 hours in a preservative-free amber polyethylene 24-hr urine collection container (with no metal caps or glued inserts).
- Refer to Mayo Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for additional information on acceptable collection conditions.
- Specimen must be refrigerated within 4 hours of completion of 24-hr collection.
- Random Urine: Collect random urine in a sterile screw-cap container (with no metal cap or glued insert).
- 24 Hour Urine Collection (Preferred):
- Handling Instructions
Outside Laboratories:
- Mix urine. Measure and record total volume. Note the collection interval and total volume on the requisition.
- Aliquot urine into a Mayo metal-free screw-capped vial (T173) and refrigerate.
- Note: Mayo T173 is recommended, but not required.
Stability (24-Hour): Refrigerated (preferred): 28 days; Ambient: 28 days; Frozen: 28 days.
Stability (Random): Refrigerated (preferred): 28 days; Ambient: 14 days; Frozen: 28 days.
- Quantity
-
requested: 10 mL urine
minimum: 2 mL urine (24-Hour); 1.5 mL urine (Random)
Processing
- Processing
SPS: Specimen must be refrigerated within 4 hours of completion of 24-hour collection.
- 24-Hour Collection: Mix specimen well. Measure and record total volume. Aliquot urine into a Mayo metal-free screw-capped vial (T173)* and refrigerate.
- Random Urine: Aliquot urine into a Mayo metal-free screw-capped vial (T173)* and refrigerate.
*Note: Mayo T173 is recommended, but not required.
Sendouts:
- 24-Hour Collection: Order Mayo Test: CDU.
- Random Collection: Order Mayo Test: CDUCR (Cadmium/Creatinine Ratio, Rand Urine).
- Batch RUCD on the interface. Add test CDUCR and delete test CDU in MayoAccess prior to closing the batch.
Stability (24-Hour): Refrigerated (preferred): 28 days; Ambient: 28 days; Frozen: 28 days.
Stability (Random): Refrigerated (preferred): 28 days; Ambient: 14 days; Frozen: 28 days.
Performance
- LIS Dept Code
- Sendouts Mayo Lab (RF) (MARF)
- Performing Location(s)
-
Sendout Mayo Clinic Laboratories (Superior Drive)
800-533-17103050 Superior Drive NW
Rochester, MN 55901 - Frequency
- Performed: Monday - Friday. Report Available: 1-3 days.
- Available STAT?
- No
Billing & Coding
- CPT codes
- 82300
- LOINC
- 21130-0
- Interfaced Order Code
- UOW2132