Osteocalcin

General Information

Lab Name
Osteocalcin
Lab Code
ROCAL
Epic Name
Osteocalcin
External Test Id
OSCAL
Description

Useful For:

  • Monitoring and assessing effectiveness of antiresorptive therapy in patients treated for osteopenia, osteoporosis, Paget's disease, or other disorders in which osteocalcin levels are elevated
  • As an adjunct in the diagnosis of medical conditions associated with increased bone turnover, including Paget's disease, cancer accompanied by bone metastases, primary hyperparathyroidism, and renal osteodystrophy

This test is not useful for the diagnosis of osteoporosis.

Patient Preparation:

  • For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.
  • Patient should be fasting for 12 hours.
Synonyms
BGP, Bone GLA Protein, N-MID Osteocalcin
Components

Interpretation

Method

Electrochemiluminescence Immunoassay

Reference Range
Units: ng/mL
Female Male Unknown
AgeRange AgeRange AgeRange
0-4y14-126 0-4y19-75
5y-9y16-152 5y-9y21-108
10y-15y15-151 10y-15y19-159
16y-17y9-70 16y-17y12-114
18y-9-42 18y-9-42

Effective date: 07/28/2020

Ordering & Collection

Specimen Type
Blood
Collection

3 mL blood in RED TOP tube or GOLD SST

Handling Instructions

Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic aliquot. Freeze serum at -20°C.

Stability: Frozen (preferred): 90 days; Refrigerated: 14 days; Ambient: 72 hours.

Reject Due To: Gross hemolysis.

Quantity
Requested: 1.0 mL serum
Minimum: 0.75 mL serum

Processing

Receiving Instructions

Centrifuge sample and transfer serum to a separate plastic vial. Freeze serum at -20°C.

Sendouts, order Mayo Test: OSCAL.

Stability: Frozen (preferred): 90 days; Refrigerated: 14 days; Ambient: 72 hours.

Reject Due To: Gross hemolysis.

Misc Sendout

Performance

Lab Department
Sendouts Mayo Lab (FZ)(MAFZ)
Frequency
Performed: Monday - Friday, 5 a.m.-12 a.m. and Saturday, 6 a.m.-6 p.m. Analytic Time: 1 day.
Available STAT?
No
Performing Location(s)
Sendout Mayo Clinic Laboratories (Superior Drive)
800-533-1710

3050 Superior Drive NW
Rochester, MN 55901

Billing & Coding

CPT Codes
83937
LOINC
2697-1
Interfaced Order Code
UOW2052
Interfaced Result Code
UOW2052