Hypersensitivity Pneumonitis Mold and Bacteria IgG Panel (Sendout)
General Information
- Lab Name
- Hypersensitivity Pneumonitis Panel
- Lab Code
- RHYPP
- Epic Name
- Hypersensitivity Pneumonitis Panel (Sendout)
- External Test Id
- FHSPP
- Description
Clinical Utility: Hypersensitivity pneumonitis (HP) or extrinsic allergic alveolitis is a diffuse inflammation of the peripheral airways of the lung. It is caused by repeated inhalation of a variety of organic dust allergens including animal and vegetable products, fungi and bacteria. Frequently the etiologic agents are associated with the patient's occupational environment. Tests included in this panel: Alternaria tenuis/alternata IgG, Aspergillus fumigatus IgG, Aureobasidium pullulans IgG, Laceyella sacchari IgG, Micropolyspora faeni IgG, Penicillium Chrysogenum/notatum IgG, Phoma betae IgG, Trichoderma viride IgG. Thermoactinomyces vulgaris IgG is no longer included in this panel as of 06/06/2022.
- References
- Mayo Clinical & Interpretive Information: Hypersensitivity Pneumonitis Panel
- Synonyms
- Allergic Lung Serology, Farmer's Lung Antibody, FHPP2, FHSPP, HP Panel
- Components
-
Code Name RHYPPN Hypersensitivity Pneumonitis Panel (Sendout) RHYPAT Alternaria tenuis/alternata IgG RHYPAF Aspergillus fumigatus IgG RHYPAP Aureobasidium pullulans IgG RHYPLS Laceyella sacchari IgG RHYPMF Micropolyspora faeni IgG RHYPPC Penicillium Chrysog/notatum IgG RHYPPB Phoma betae IgG RHYTRV Trichoderma viride IgG UW425 Study: Hyper. Pneumonitis
Interpretation
- Method
Immunoassay FEIA
- Reference Range
- See individual components
- Ref. Range Notes
Reference Values:
Alternaria tenuis/alternata IgG: <12.0 mcg/mL Aspergillus fumigatus IgG: <46.0 mcg/mL Aureobasidium pullulans IgG: <18.0 mcg/mL Laceyella sacchari IgG: <25.0 mcg/mL Micropolyspora faeni IgG: <5.0 mcg/mL Penicillium Chrysogenum/notatum IgG <22.0 mcg/mL Phoma betae IgG: <8.0 mcg/mL Trichoderma viride IgG: <10.0 mcg/mL Antibody levels greater than the reference range indicate that the patient has been immunologically sensitized to the antigen. The significance of elevated IgG depends on the nature of the antigen and the patient's clinical history.
Ordering & Collection
- Specimen Type
- Blood
- Collection
-
Collect 3 mL blood in a RED TOP tube or GOLD TOP SST
- Handling Instructions
Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum while awaiting shipment. Transport with a cold pack.
Stability: Refrigerated (Preferred): 28 days; Frozen: 28 days; Ambient: 7 days.
Reject Due To: Gross hemolysis.
- Quantity
-
Requested: 0.6 mL serum for RHYPPN + 1 mL serum for UW425
Minimum: 0.5 mL serum for RHYPPN
Processing
- Receiving Instructions
Centrifuge sample and transfer serum to two separate plastic vials. If sample volume is low, prioritize the sendout test (RHYPPN).
- RHYPPN: Refrigerate sample (Mayo Sendouts Rack).
- UW425: Freeze sample at -20°C (Immunology rack).
Sendouts:
- Order Mayo Test: FHSPP
- Interfaced: Yes [Interface: 601; Worksheet: MARF]
Stability: Refrigerated (Preferred): 28 days; Frozen: 28 days; Ambient: 7 days.
Reject Due To: Gross hemolysis.
- Misc Sendout
Performance
- Lab Department
- Frequency
- Performed: Monday through Friday. Reported: 2-7 days from sample receipt at Mayo Clinic Labs.
- Available STAT?
- No
- Performing Location(s)
-
Sendout Mayo forwards to Eurofins Viracor
800-533-171018000 W. 99TH Street
Lenexa, KS 66219
Billing & Coding
- CPT Codes
- 86001x8
- LOINC
- 35577-6
- Interfaced Order Code
- UOW5599