Dengue Fever IgG and IgM Antibody (Sendout)

General Information

Lab Name

Lab Code

RDFAGM

Epic Name

Dengue Fever IgG and IgM Antibody (Sendout)

External Test Id

0093096

Description

Ordering Recommendation: May aid in the diagnosis of dengue when timing of infection is uncertain. Testing should also be considered for other arthropod-borne viruses with similar symptomology based on clinical presentation and travel history.

Collection Note: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Specimens must be plainly marked as "acute" or "convalescent."

Synonyms

0093096, Arbovirus, DENGUE AB, Dengue Fever Ab Panel, Dengue Fever Antibodies, Flavivirus

Components

Code	Name
RDFAGR	Dengue Fever IgG Antibody
RDFAMR	Dengue Fever IgM Antibody

Interpretation

Guidelines

Washington DOH Notifiable Conditions

Method

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reference Range

See individual components

Ref. Range Notes

Dengue Fever Virus Antibody, IgG:

Value:	Interpretation:
1.64 IV or less:	Negative - No significant level of detectable dengue fever virus IgG antibody.
1.65-2.84 IV:	Equivocal - Questionable presence of antibodies. Repeat testing in 10-14 days may be helpful.
2.85 IV or greater:	Positive - IgG antibody to dengue fever virus detected, which may indicate a current or past infection.

Dengue Fever Virus Antibody, IgM:

Value:	Interpretation:
1.64 IV or less:	Negative - No significant level of detectable dengue fever virus IgM antibody.
1.65-2.84 IV:	Equivocal - Questionable presence of antibodies. Repeat testing in 10-14 days may be helpful.
2.85 IV or greater:	Positive - IgM antibody to dengue fever virus detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Ordering & Collection

Specimen Type: Blood
Collection: Collect 3 mL blood in GOLD SST or RED TOP tube
Handling Instructions: Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year; Ambient: 48 hours. Avoid repeated freeze/thaw cycles.

Unacceptable Conditions: Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
Quantity: Requested: 1 mL serum
Minimum: 0.1 mL serum

Processing

Receiving Instructions

Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

Sendouts:

Order ARUP Test: 0093096.
Interfaced: Yes. [Interface Number: 602; Department: ARPR]
If parallel testing will be performed:
- Mark serum samples as "acute" or "convalescent," as appropriate. Convalescent samples must be received by ARUP within 30 days from receipt of the acute sample.
- For the convalescent order, enter instructions in the modifier before batching sample. Comment: Run parallel testing with acute sample collected (MM/DD/YY).

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year; Ambient: 48 hours. Avoid repeated freeze/thaw cycles.

Unacceptable Conditions: Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

Misc Sendout

Performance

Lab Department

Sendouts ARUP Lab (RF)(ARPR)

Frequency

Performed: Monday, Wednesday, Friday. Reported: 1-5 days.

Available STAT?

Performing Location(s)

Sendout	ARUP Laboratories, Inc. 800-522-2787 500 Chipeta Way Salt Lake City, UT 84108

Billing & Coding

CPT Codes: 86790x2
LOINC: 41878-0
Interfaced Order Code: UOW4948