URD RB Ab Panel (1st)(Sendout)

Indications: Red blood cell antibody specificity is determined by reacting patient serum with extended panel of reagent red blood cells of known RBC phenotype. Clinically significant alloantibodies (e.g., Rh, Kell, Duffy, Kidd) may be present in patients with hemolytic transfusion reactions or hemolytic disease of the newborn. The clinical significance of some of the more commonly encountered red cell alloantibodies are summarized in the Clinically Significant Red Cell Antibodies table. Autoantibodies usually react with all panel cells (i.e., “panagglutinins”), and are present in the sera of ~80% of patients with warm (IgG) autoimmune hemolytic anemia. Red cell alloantibodies may require several techniques for final identification. The presence of an autoantibody may require a series of absorptions and elutions to determine the presence of underlying alloantibodies.

Test Information: This test panel may include other tests such as DAT, elution, adsorptions and RBC genotyping depending on the complexity of the workup. Additional fees may apply.

Ordering Note: Ordered by CAST for billing reconciliation.

20 mL blood in EDTA LAVENDER TOP tubes or RED TOP tubes

Pediatric: 1 full 3 ml EDTA; neonate: 2 full 0.5 ml EDTA microtainers