CMV IgG Avidity (Sendout)

General Information

Lab Name

Lab Code

RCMVAV

Epic Name

CMV IgG Avidity (Sendout)

External Test Id

FCYTG

Description

Clinical Information: Discrimination between recent (primary) and past cytomegalovirus (CMV) infection can be an important tool in the clinical management of pregnant women. Although nearly all individuals with recent CMV infection are positive for CMV IgM, individuals with past CMV may also express CMV IgM due to long-term IgM persistence or viral reactivation; thus, detection of CMV IgM is not a reliable indicator of recent CMV infection. Measurement of CMV IgG avidity can assist in discriminating recent from past CMV infection. A low avidity index is a reliable indicator of CMV infection within the previous 6 months, a high avidity index essentially excludes the possibility that infection occurred within the previous 4 months. Avidity index values should be considered within the context of other laboratory findings and clinical signs.

Synonyms

CMV Avidity, Cytomegalovirus IgG Avidity by ELISA, FCYTG

Components

Code	Name
RCMVAI	CMV IgG Avidity Index

Interpretation

Reference Range

See individual components

Ref. Range Notes

Reference Value: >0.70

Interpretation:

< 0.60	Low Avidity Index
0.60 - 0.70	Intermediate Avidity Index
>0.70	High Avidity Index

Ordering & Collection

Specimen Type: Blood
Collection: 3 mL blood in RED TOP tube or GOLD SST
Handling Instructions: Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.

Stability: Refrigerated (preferred): 14 days; Frozen: 30 days; Ambient: 7 days.

Reject Due To: Gross hemolysis (mild okay).
Quantity: Requested: 1 mL serum
Minimum: 0.5 mL serum

Processing

Receiving Instructions

Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.

Sendouts:

Order Mayo Test: FCYTG.
Interfaced: Yes. [Interface: 601; Department: MARF]

Stability: Refrigerated (Preferred): 14 days; Frozen: 30 days; Ambient: 7 days.

Reject Due To: Gross hemolysis (mild okay).

Misc Sendout

Performance

Lab Department

Sendouts Mayo Lab (RF)(MARF)

Frequency

Performed: Sunday, Tuesday through Friday. Report Available: 4-10 days from sample receipt at the performing lab.

Available STAT?

Performing Location(s)

Sendout	Mayo forwards to Quest Diagnostics Nichols Institute 800-533-1710 33608 Ortega Highway San Juan Capistrano, CA 92675

Billing & Coding

CPT Codes: 86644
LOINC: 52984-2
Interfaced Order Code: UOW5597