Bordetella pertussis IgG Antibodies (Sendout)
General Information
- Lab Name
- Bordetella Pertussis IgG Antibody (Sendout)
- Lab Code
- RBPIGG
- Epic Name
- Bordetella pertussis IgG Antibody (Sendout)
- External Test Id
- BORDG
- Description
Useful For:
- Diagnosis of recent infection with Bordetella pertussis in patients with symptoms consistent with whooping cough for 2 or more weeks
- This test should not be used in neonates, young infants or in children between the ages of 4 to 7 years as the routine childhood vaccine schedule may interfere with result interpretation.
- This test should not be used as a test of cure, to monitor response to treatment, or to determine vaccine status.
Test Information:
- This test may be used to diagnose recent infection with Bordetella pertussis in patients who have not had the acellular pertussis vaccine or booster in the last 6 months.
- Synonyms
- B. pertussis, B. pertussis Ab, BORDG, Whooping cough
- Components
-
Code Name RPERTG Bordetella pertussis IgG Antibody RPERTV Bordetella pertussis IgG Antibody Value
Interpretation
- Guidelines
- Method
Enzyme-Linked Immunosorbent Assay (ELISA)
- Reference Range
- See individual components
- Ref. Range Notes
Reference Values: <40 IU/mL
Interpretation:
Negative (<40 IU/mL): No IgG antibodies to pertussis toxin (PT) detected. Results may be falsely negative in patients with less than 2 weeks of symptoms. Borderline (40-<100 IU/mL):
Recommend follow-up testing in 10 to 14 days if clinically indicated. Positive (> or =100 IU/mL): IgG antibodies to pertussis toxin (PT) detected. Results suggest recent infection with or recent vaccination against Bordetella pertussis. - Interferences and Limitations
Cautions:
Immune response following vaccination cannot be distinguished from recent infection.
For diagnosis, clinical symptoms, the patient's age and vaccination history should always be taken into account along with the serological results.
Whooping cough caused by Bordetella parapertussis will not be detected by this assay.
The Centers for Disease Control and Prevention recommend nucleic acid amplification tests (NAAT) or culture as first-line tests for B pertussis infection. However, serologic testing may be useful in patients who are symptomatic for more than 2 weeks.
Ordering & Collection
- Specimen Type
- Serum
- Collection
-
Collect 3 mL blood in RED TOP tube or GOLD SST
- Handling Instructions
Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.
Stability: Refrigerated (preferred): 30 days; Frozen 30 days; Ambient: Unacceptable.
Reject Due To: Gross hemolysis, gross lipemia, gross icterus, heat-inactivated.
- Quantity
-
Requested: 1 mL serum
Minimum: 0.5 mL serum
Processing
- Receiving Instructions
Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.
Sendouts:
- Order Mayo Test: BORDG.
- Interfaced: Yes.
Stability: Refrigerated (preferred): 30 days; Frozen 30 days; Ambient: Unacceptable.
Reject Due To: Gross hemolysis, gross lipemia, gross icterus, heat-inactivated.
- Misc Sendout
Performance
- Lab Department
- Sendouts Mayo Lab (RF)(MARF)
- Frequency
- Performed: Thursday. Report Available: 1-7 days.
- Available STAT?
- No
- Performing Location(s)
-
Sendout Mayo Clinic Laboratories (Superior Drive)
800-533-17103050 Superior Drive NW
Rochester, MN 55901
Billing & Coding
- CPT Codes
- 86615
- LOINC
- 42330-1
- Interfaced Order Code
- UOW4937