Acetylcholine Receptor (Muscle) Binding Antibody (Sendout)

General Information

Lab Name

ACh Receptor (Muscle) Binding Antibody (Sendout)

Lab Code

RACHRM

Epic Name

ACh Receptor (Muscle) Binding Antibody (Sendout)

External Test Id

ARBI

Description

This is the primary diagnostic test for Myasthenia Gravis.

Useful For:

A first-order test for the laboratory diagnosis of myasthenia gravis (MG)
Detecting "subclinical MG" in recipients of D-penicillamine, in patients with thymoma without clinical evidence of MG, and in patients with graft-versus-host disease
Distinguishing acquired disease (90% positive) from congenital disease (negative)
Monitoring disease progression in MG or response to immunotherapy
An adjunct to the test for P/Q-type calcium channel binding antibodies as a diagnostic aid for Lambert-Eaton myasthenic syndrome (LES) or primary lung carcinoma

Ordering Notes:

Synonyms

Acetylcholine Receptor Binding Antibody, ACHR Binding Ab, ARBI, Myasthenia gravis

Components

Method

Radioimmunoassay (RIA)

Reference Range

Units: nmol/L

Female		Male
Age	Range	Age	Range
0-	0-0.02	0-	0-0.02

Effective date: 01/20/2005

Specimen Type: Blood
Collection: 6 mL blood in RED or GOLD SST
Handling Instructions: Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.

Stability: Refrigerated (preferred): 28 days; Frozen: 28 days; Ambient: 72 hours.

Reject Due To: Gross hemolysis, lipemia, or icterus.
Quantity: Requested: 1.5 mL serum
Minimum: 1 mL serum

Receiving Instructions

Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.

Sendouts:

Stability: Refrigerated (preferred): 28 days; Frozen: 28 days; Ambient: 72 hours.

Reject Due To: Gross hemolysis, lipemia, or icterus.

Lab Department

Sendouts Mayo Lab (RF)(MARF)

Frequency

Performed: Monday - Sunday. Report Available: 3-6 days.

Available STAT?

Performing Location(s)

Sendout	Mayo Clinic Laboratories 800-533-1710 200 First Street Southwest Rochester, MN 55901