Amino Acids, Plasma (Sendout)
General Information
- Lab Name
- Amino Acids, PLASMA
- Lab Code
- RAA
- Epic Name
- Amino Acids, Plasma
- External Test Id
- LAB811
- Description
Description: Measurement of 25 amino acids by ion exchange chromatography. This test includes the following: Taurine, Aspartic Acid, Hydroxyproline, Threonine, Serine, Asparagine, Glutamic Acid, Glutamine, Proline, Glycine, Alanine, Citrulline, Valine, Cystine, Methionine, Alloisoleucine, Isoleucine, Leucine, Tyrosine, Phenylalanine, Homocystine, Ornithine, Lysine, Histidine, Arginine.
Clinical Utility: Amino acid analysis can be useful in the clinical work up, diagnosis, or dietary monitoring of the following disorders: Phenylketonuria, tyrosinemia, maple syrup urine disease, urea cycle defects (argininosuccinic aciduria, argininemia, CPS, OTC deficiency, citrullinemia), non-ketotic hyperglycinemia, homocystinuria, defects of cobalamin metabolism, cystinuria (urine only), ornithinemia, and lysinuric protein intolerance. Amino acid analysis is also performed for nutritional monitoring.
Ordering Requirements: Include relevant clinical information (drug therapy, family history, etc.) in the Epic order comment to ensure proper interpretation.
- References
- Seattle Children's Hospital Laboratory Test: Amino Acids Quant, Plasma
- Synonyms
- AAQNT, Alanine, Alloisoleucine, Arginine, Asparagine, Aspartic Acid, Citrulline, citrullinemia, Cystine, Glutamic Acid, Glutamine, Glycine, Histidine, Homocystine, Hydroxyproline, hyperglycinemia, Isoleucine, LAB811, Leucine, Lysine, Methionine, NKH, Ornithine, Phenylalanine, Proline, Serine, Taurine, Threonine, Tyrosine, Valine
- Components
-
Code Name RTAU Taurine RASP Aspartic Acid RHYP Hydroxyproline RTHR Threonine RSER Serine RASN Asparagine RGLA Glutamic Acid RGLN Glutamine RPLN Proline RGLY Glycine RALAN Alanine RCIT Citrulline RVALN Valine RCYST Cystine RMTH Methionine RALEU Alloisoleucine RILE Isoleucine RLEU Leucine RTYR Tyrosine RPHE Phenylalanine RHOM Homocystine RORN Ornithine RLYS Lysine RHIS Histidine RARG Arginine RNTRP1 Amino Acid Interpretation OLDIS1 Outside Laboratory Disclaimer
Interpretation
- Method
Ion exchange chromatography with post column derivatization
- Reference Range
- See individual components
- Ref. Range Notes
Refer to Plasma Amino Acid Reference Ranges.
- Interferences and Limitations
Note: Amino Acids performed on urine samples is not clinically indicated.
- References
- Seattle Children's Hospital Laboratory Test: Amino Acids Quant, Plasma
Ordering & Collection
- Specimen Type
- Blood
- Collection
-
3 mL blood in DARK GREEN (Na Heparin) or LIME GREEN PST (Lithium Heparin)
Also Accepted: RED or LAVENDER TOP (EDTA) tube. Note: Serum or EDTA plasma is acceptable, but not preferred.
Collection Timing: For infants and children, draw sample prior to feeding or 2-3 hours after a meal.
- Handling Instructions
Outside Laboratories: Centrifuge sample and transfer plasma/serum to a separate plastic vial within one hour of collection. Freeze plasma/serum at -20°C while awaiting shipment. Transport on dry ice.
- Optional: To ensure proper interpretation, include relevant clinical information (drug therapy, and family history) on the DLMP requisition.
Stability: Frozen (preferred): 1 month; Refrigerated: 24 hours; Ambient: 2 hours.
- Quantity
-
Requested: 1 mL plasma or serum
Minimum: 0.5 mL plasma or serum
Processing
- Receiving Instructions
Centrifuge sample and transfer plasma/serum to a separate plastic vial within one hour of collection. Freeze plasma/serum at -20°C.
SPS, order this test on a separate accession.
Sendouts:
- Order SEACHL Test: LAB811
- Interfaced: Yes [Interface: 601; Department: SOSC]
- If clinical information (drug therapy, family history) is included in the order, print the Epic requisition and send it with a copy of the MayoAccess Batch Sheet.
- Send samples on dry ice via DLMP or DE courier.
Stability: Frozen: 1 month; Refrigerated: 24 hours; Ambient: 2 hours.
- Misc Sendout
Performance
- Lab Department
- SCHL Interfaced Sendouts(SOSC)
- Frequency
- Performed: Monday through Friday. TAT: 2-5 days from sample receipt at Seattle Children's Lab.
- Available STAT?
- No
- Performing Location(s)
-
Sendout Seattle Children's Hospital Laboratories
206-987-26174800 Sand Point Way NE
Seattle, WA 98105Room Number: FB.2.441
- Other Locations/Notes
Seattle Children's Hospital Laboratory, Biochemical Genetics: 206-987-2216
Billing & Coding
- CPT Codes
- 82139
- LOINC
- 12468-5
- Interfaced Order Code
- UOW5040