BCR/ABL p190, Quant by RT PCR

General Information

Lab Name

BCR/ABL p190, Quant by RT PCR

Lab Code

QP190

Epic Name

BCR/ABL p190 Quantitative

Description

The Philadelphia chromosome (Ph) is the product of the reciprocal translocation between the ABL1 gene on chromosome 9, and the BCR gene on chromosome 22. Depending on variations in splicing, the BCR exon 1 can join to the ABL1 exon 2, resulting in the p190 (e1:a2) BCR/ABL1 breakpoint. p190 is found almost exclusively in Ph+ALL patients, but can, on occasion, be found in CML patients as an alternative splice variant. Our p190 assay is a laboratory-developed test using real- time quantitative PCR.

Reportable Range: 0.01 – 100%
Limit of Detection: 0.002%
Limit of Quantification: 0.01%
Precision near LOD (CV): 24%

Stability is 4 days, specimens received after 4 days will be rejected.

Hematopathology test request form can be found at Request Form.

Forms & Requisitions

Requisition

Synonyms

B-ALL, B-Cell Acute Lymphoblastic Leukemia, BALL, P190, QP190, Quantitative BCR/ABL p190, t(9;22)

Components

Code	Name
P190SD	BCR/ABL p190 Specimen Desc
P190RS	BCR/ABL p190, Quant by RT PCR
P190RA	BCR/ABL p190 Ratio %
P190IN	BCR/ABL p190 Interpretation
P190M	BCR/ABL p190 Method
P190GR	P190 Case Number