Factor V Activity

General Information

Lab Name: Factor V Activity
Lab Code: F5
Epic Name: Factor V Activity (Not for thrombosis eval - see APCR)
Description: This test is NOT for Factor V Leiden or F5DNA. Please see APCR (Factor V Leiden Protein Assay) or F5DNA (Factor V DNA Screen) for those respective tests.

Factor 5 activity is used for diagnosing rare congenital deficiencies of coagulation factor V, investigation of prolonged prothrombin time and evaluating acquired deficiencies associated with liver disease, intravascular coagulation and fibrinolysis.
Forms & Requisitions: Outside clients should fill and submit Coagulation Patient Clinical History Form: Coagulation Patient Clinical History Form
Synonyms: Factor 5, Factor V
Components

Interpretation

Method

Stago STA Clottable Factor assay

Reference Range

Units: %

Female		Male
Age	Range	Age	Range
0-	50-150	0-	50-150

Interferences and Limitations

Patients on bivalirudin (Angiomax), dabigatran (Pradaxa), argatroban (Novastan), rivaroxaban (Xarelto), apixaban (Eliquis), and edoxaban (Savaysa) may show prolonged clotting times. This may cause an under- estimation of the factor concentrations.

Ordering & Collection

Specimen Type: Blood
Collection: 3 or 5 mL BLUE TOP (CITRATE) tube
Forms & Requisitions: Outside clients should fill and submit Coagulation Patient Clinical History Form: Coagulation Patient Clinical History Form
Handling Instructions: The Laboratory MUST process specimen, within 4 hrs of blood collection
Quantity: Requested: entire specimen

Processing

Receiving Instructions: UW-MT Instructions: Take specimen to UW-MT Coag lab for processing. Coag Tech will freeze plasma sample for transport to HMC Coag.

HMC Instructions: Take specimen to HMC Coag lab for processing.

Outside Laboratory: Centrifuge for 10 minutes, remove plasma & re-spin plasma for another 10 minutes. Decant & Freeze plasma (minimum 1.0 mL) @ -20°C to -80°C. Send frozen on dry ice.

Misc Sendout

Performance

Lab Department

Coagulation(COAG)

Frequency

Run Monday-Friday. Reported by end of day.

Available STAT?

Performing Location(s)

HMC	Coagulation 206-520-4600 325 9th Ave, Rm # GWH-47, Seattle, WA 98104-2420

Billing & Coding

CPT Codes: 85220
LOINC: 3193-0
Interfaced Order Code: UOW1289
Interfaced Result Code: UOW1289