Cryoglobulins
General Information
- Lab Name
- Cryoglobulins
- Lab Code
- CRYOG
- Epic Name
- Cryoglobulins
- Description
Use this mnemonic when only Cryoglobulin requested.
This assay detects the presence of a cryoglobulin, and if present, provides a semi quantitative estimate of the amount. Cryoglobulins are associated with a variety of clinical conditions including: myeloma, Waldenstrom's macroglobulinemia, chronic lymphocytic leukemia, rheumatoid arthritis, Sjogren's syndrome, mixed essential cryoglobulinemia, systemic lupus erythematosus, infectious mononucleosis, cytomegalovirus infections, acute viral hepatitis, primary biliary cirrhosis, post streptococcal glomerulonephritis, infective endocarditis, leprosy, kalaazar, and tropical splenomegaly syndrome.
- Components
-
Code Name CRYO Cryoglobulin, Serum at 3 day CRYO10 Cryoglobulin, Serum at 10 day CRYMTH Cryoglobulins Method
Interpretation
- Method
Precipitation (Passive precipitation at refrigerator temperature, that is reversible when warmed to 37°C)
- Reference Range
- See individual components
Ordering & Collection
- Specimen Type
- Blood
- Collection
-
15 mL blood in RED TOP tubes. Specimen must be maintained at 37°C after collection.
- Handling Instructions
Keep samples warm and transport to lab IMMEDIATELY. Suggest transporting specimens maintained at 37°C, possibly under your arm with specimen tube securely enclosed in a specimen transport bag. Specimen will be rejected if clotted. Not to be drawn on blood draw rounds.
- Quantity
-
Requested: 5 mL serum
Minimum: 3 mL serum
Processing
- Receiving Instructions
UW-MT Instructions
Specimen MUST be kept at 37°C until received by COAG Lab. COAG: Put "unclotted" specimen in 37°C waterbath to clot for 1-2 hours to prevent CRYOGLOBULINS from being trapped in clot. After clotting is complete, spin & aliquot serum while serum is still warm. Return sample to the refrigerator in SPS. Do Not Freeze.
HMC Instructions
Specimen MUST be kept at 37°C until received by SPS. SPS will put "unclotted" specimen in 37°C waterbath to clot for 1-2 hours to prevent CRYOGLOBULINS from being trapped in clot. After clotting is complete, spin & aliquot serum while serum is still warm. Refrigerate serum. Do not freeze.
Outside Lab Instructions
Specimen MUST be kept at 37°C until received in the lab. The lab will put "unclotted" specimen in 37°C waterbath to clot for 1-2 hours to prevent CRYOGLOBULINS from being trapped in clot. If a waterbath is not available, a 37°C heat block is acceptable. After clotting is complete, spin & aliquot serum while serum is still warm. Refrigerate serum. Do not freeze.
- Misc Sendout
Performance
- Lab Department
- Immunology(IMM)
- Frequency
- Monday-Friday, results in 10 days
- Available STAT?
- No
- Performing Location(s)
-
UW-MT Immunology
206-520-4600Clinical Lab, Room NW220,
University of Washington Medical Center,
1959 NE Pacific street, Seattle, WA 98195
Billing & Coding
- CPT Codes
- 82595
- LOINC
- 15174-6
- Interfaced Order Code
- UOW1135