Periprosthetic Joint Infection (PJI) Detection (Sendout)

single page view

General Information

Lab Name
Lab Code
932
External Test Id
7002
Description

Ordering Recommendation: The Synovasure® Alpha Defensin ELISA test performed on synovial fluid may be used as an adjunct to aid in the diagnosis of periprosthetic joint infection (PJI). Effective April 1st, 2024, this assay no longer includes C-reactive Protein (CRP). The final result is provided as a qualitative result: Positive, Negative or Indeterminate.

Synonyms
Alpha defensin, Alpha-defensin, Periprosthetic Joint Infection Detection, PJI Detection, SYNOVA PJI, Synovasure
Components

Interpretation

Method

Qualitative Enzyme-Linked Immunosorbent Assay

Reference Range

Ordering & Collection

Specimen Type
Fluid
Collection

Collect 1 mL Synovial Fluid in a RED TOP tube. The specimen source (eg., left knee, right shoulder, etc.) is required.

  • Note: Separate specimens must be submitted when multiple tests are ordered.
Handling Instructions

Outside Laboratories: Due to the limited stability of the sample, it is recommended that outside facilities arrange for testing directly with CD Laboratories. If submitting through University of Washington, expedite transport. Samples must arrive at the performing lab within 4 days of collection (allow for an extra day of transport from UW-MT to CD Labs).

  • Indicate the aspiration site (left/right hip/knee/other) on the UW-MT requisition.

Specimen: Refrigerate fluid.

Stability: Refrigerated (preferred): 4 days; Ambient: 72 hours; Frozen: Unacceptable.

Quantity
Requested: 1 mL Synovial Fluid
Minimum: 0.5 mL Synovial Fluid

Processing

Receiving Instructions

Refrigerate specimen in original collection container.

Login: SEND1-;REFRIG

  • RSNDT1: CDLAB
  • RSTYP1: SYN
  • RTSRQ1: ;Synovasure Alpha Defensin for Periprosthetic Joint Infection (PJI)

Sendouts:

  • Order CD Laboratories Test: 7002 (Synovasure Alpha Defensin ELISA for PJI).
  • Indicate the specimen source on the requisition.
  • Samples must be received at CD Labs within 4 days of collection.
  • Samples may be shipped on Fridays using the FedEx 'Saturday Delivery' option.

Stability: Refrigerated (preferred): 4 days; Ambient: 72 hours; Frozen: Unacceptable.

Misc Sendout

Performance

Lab Department
Frequency
Performed: Varies. Reported: 3-4 days.
Available STAT?
No
Performing Location(s)
Sendout CD Laboratories, Inc.
888-981-8378

810 Gleneagles Court
Suite 100
Baltimore, MD 21286

Fax: (410) 415-1951

Email: customerservice@cdlaboratories.com

Billing & Coding

Billing Comments

CPTs: 83516