Mucopolysaccharides Quantitative, Urine (Sendout)

Test Description: Quantitative DMB dye binding test used to screen individuals suspected of having a mucopolysaccharidosis.

Ordering Guidance: This test is suitable for initial assessments where elevated GAG levels along with low enzyme activities strongly suggest MPS. For monitoring of disease progression and treatment efficacy in patients with known MPS IV, refer to separate test Morquio Syndrome (MPS IV) Monitoring, Urine (Sendout).

Ordering Requirements: Include relevant clinical information (drug therapy, family history, etc.) in the Epic order comment to ensure proper interpretation.

Reference Ranges:

Outside Laboratories:

• Transfer 2 mL urine (1 mL minimum) to a separate, screw-cap urine aliquot, leaving room at the top for expansion.
• Freeze urine at -20°C while awaiting shipment. Transport on dry ice.
• Optional: Include relevant clinical information (diet/TPN therapy, drug therapy, family history) in the "Comments" section of the DLMP requisition.

Stability: Frozen (preferred): 3 weeks; Refrigerated: 2 days; Ambient: 24 hrs.

Transfer 2 mL urine (1 mL minimum) to a separate, screw-cap urine aliquot vial, leaving room at the top for expansion. Freeze urine at -20°C.

Login: SEND1-;FREEZE URINE

• RSNDTO: SEACHL
• RSPTYP: URN
• RTSTRQ: ;Mucopolysaccharides Quant, Urine (SEACHL Test LAB1057)

Sendouts:

• Order SEACHL Test: LAB1057
• Complete a SEACHL Biochemical Genetics requisition and select test, "Mucopolysaccharide, Quantitative Urine" under the "Urine" section.
• If clinical information (drug therapy, family history) is included with the order (optional), print the Epic requisition and send it with the SEACHL form.
• Send samples on dry ice via DLMP or DE courier.

Stability: Frozen (preferred): 3 weeks; Refrigerated: 2 days; Ambient: 24 hrs.