Chitotriosidase Enzyme Analysis (Sendout)

single page view

General Information

Lab Name
Lab Code
428
External Test Id
BCHI
Description

Useful For: This test measures chitotriosidase enzyme activity and can be used to monitor disease progression in patients with certain lysosomal storage disorders such as Gaucher disease and Acid sphingomyelinase deficiency.

Test Information: Chitotriosidase enzyme activity is measured by using a 4-methylumbelliferyl (4-MU) substrate.

References
Forms & Requisitions
Synonyms
Acid Sphingomyelinase, BCHI, CHITO, Chitotriosidase activity, Gaucher disease
Components

Interpretation

Method

4-MU plasma enzyme method

Reference Range
Ref. Range Notes
Reference Range: 0.00 - 200.00 nmol/hr/mL plasma
References

Ordering & Collection

Specimen Type
Blood
Collection

3 mL blood in GREEN TOP (Sodium Heparin) tube

Forms & Requisitions
Handling Instructions

Outside Laboratories:

  • Centrifuge sample and aliquot 1 mL plasma to a separate plastic vial. Freeze plasma at -70°C while awaiting shipment. Transport on dry ice.

Stability (Plasma): Frozen, -70°C (preferred): 2 years; Frozen, -20°C: Acceptable; Refrigerated: 24 hours; Ambient: 24 hours.

Quantity
Requested: 1 mL heparin plasma
Minimum: 1 mL heparin plasma

Processing

Receiving Instructions

Centrifuge sample and aliquot 1 mL plasma to a separate plastic vial. Freeze plasma at -70°C.

Login: SEND1-;SUPER FREEZE PLASMA

  • RSNDT1: GGC
  • RSTYP1: PLS
  • RTSRQ1: ;Chitotriosidase Enzyme Analysis (GGC Test BCHI)

Sendouts:

  • GGC Test: BCHI
  • Complete the GGC requisition. Select test "Chitotriosidase Enzyme Analysis - plasma" under "Monitoring Tests," subcategory "Gaucher, Niemann-Pick A/B" on the left side of page 3.
  • Ship FedEx Priority Overnight, Monday through Thursday only, with sufficient dry ice to ensure that samples remain frozen throughout transport.
    • Package samples as close to FedEx pickup as possible to ensure that samples remain frozen upon arrival at GGC.

Stability (Plasma): Frozen, -70°C (preferred): 2 years; Frozen, -20°C: Acceptable; Refrigerated: 24 hours; Ambient: 24 hours.

Misc Sendout

Performance

Lab Department
Frequency
Turnaround Time: 10 days from sample receipt at Greenwood Genetic Center.
Available STAT?
No
Performing Location(s)
Sendout Greenwood Genetic Center Diagnostic Laboratories
888-442-4363

106 Gregor Mendel Circle
Greenwood, SC 29646

Biochemical Genetics Laboratory Phone: (800) 473-9411
Fax: (864) 941-8141

Billing & Coding

Billing Comments

CPT: 82657