Dihydrotestosterone, Serum (Sendout)

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General Information

Lab Name
Lab Code
128
External Test Id
DHTS
Description

Useful For:

  • Monitoring patients receiving 5-alpha reductase inhibitor therapy or chemotherapy

  • Evaluating patients with possible 5-alpha reductase deficiency

References
Synonyms
5-a-dihydrotestosterone, 5-Alpha-Dihydrotestosterone, Allodihydrotestosterone, Androstanolone, DHT, DHTS, Dihydrotestosterone, Serum Dihydrotestosterone, Stanolone
Components

Interpretation

Method

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Portions of this test are covered by patents held by Quest Diagnostics.

Reference Range
Ref. Range Notes

Reference Ranges: Males

Cord blood: < or =100 pg/mL
< or =6 months: < or =1,200 pg/mL
Tanner Stages:

Mean Age Reference Range (pg/mL)
Stage I (>6 months and prepubertal) 7.1 years < or =50
Stage II 12.1 years < or =200
Stage III 13.6 years 80-330
Stage IV 15.1 years 220-520
Stage V 18 years 240-650

>19 years: 112-955 pg/mL

Reference Ranges: Females

Cord blood: < or =50 pg/mL
< or =6 months: < or =1,200 pg/mL
Tanner Stages:

Mean Age Reference range (pg/mL)
Stage I (>6 months and prepubertal) 7.1 years < or =50
Stage II 10.5 years < or =300
Stage III 11.6 years < or =300
Stage IV
12.3 years		 < or =300
Stage V 14.5 years < or =300

20-55 years: < or =300 pg/mL
>55 years: < or =128 pg/mL

Interferences and Limitations

Cautions: Patients with benign prostatic hyperplasia (BPH) or prostatic cancer may not have elevated dihydrotestosterone (DHT) levels even though growth of the prostate gland may be stimulated by DHT.

References

Ordering & Collection

Specimen Type
Blood
Collection

3 mL blood in RED TOP tube or GOLD SST

Handling Instructions

Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.

Stability: Refrigerated (preferred): 7 days; Frozen: 90 days; Ambient: Unacceptable.

Quantity
Requested: 1 mL serum
Minimum: 0.6 mL serum

Processing

Receiving Instructions

Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.

Login: SEND1-;REFRIG

  • RSNDT1: MAYOSD
  • RSTYP1: SRM
  • RTSRQ1: ;Dihydrotestosterone, Serum (Mayo Test DHTS)

Sendouts:

  • Order Mayo Test: DHTS.

Stability: Refrigerated (preferred): 7 days; Frozen: 90 days; Ambient: Unacceptable.

Misc Sendout

Performance

Lab Department
Frequency
Performed: Monday, Wednesday, Thursday, Friday. Report Available: 2-8 days.
Available STAT?
No
Performing Location(s)
Sendout Mayo Clinic Laboratories (Superior Drive)
800-533-1710

3050 Superior Drive NW
Rochester, MN 55901

Billing & Coding

Billing Comments

CPT: G0480