SARS CoV 2 Spike Antibody, IgG
- Lab Name
- SARS CoV 2 Spike Antibody, IgG
- Lab Code
- Epic Ordering
- SARS-CoV-2 Spike Antibody, IgG
The Abbott Architect SARS-CoV-2 IgG II assay, run under an emergency use authorization from the FDA, is quantitative test designed to detect IgG antibodies to the spike protein of SARS-CoV-2 in serum and plasma from individuals with an adaptive immune response to SARS-CoV-2, indicating recent or prior infection. Results are reported as AU/mL.
Reactive (Positive, ≥50.0 AU/mL) results may be due to immunization or past or present infection with SARS-CoV-2. Results from antibody testing should not be used as the sole basis to diagnose or exclude SARS-CoV-2 infection or to inform infection status.
A table of quantitative anti-spike levels for otherwise healthy, recently vaccinated individuals by week of vaccination to aid in interpretation of test results is available in Table 3 in this pre-print.
Nonreactive (Negative, <50.0 AU/mL) results do not rule out SARS-CoV-2 infection, particularly in those who have recently been in contact with the virus. Follow-up testing with a molecular diagnostic should be considered to rule out infection in these individuals. Results from antibody testing should not be used as the sole basis to diagnose or exclude SARS-CoV-2 infection or to inform infection status.
Ordering: We are pleased to perform serology testing for all patients who have a valid provider order. We recommend outside providers arrange to have their patients' blood drawn at their usual clinical draw sites and sent to the lab, preferably after contacting Client Support Services at firstname.lastname@example.org to facilitate testing.
For patients who do not regularly seek care within UW Medicine, our phlebotomists at the University of Washington Medical Center-Northwest Campus (UWMC-NW) and UWMC-NW Outpatient Medical Center (OPMC) located on Meridian Ave. N. are able to perform blood draws for testing with a valid provider order.
For Batteries containing NCVIGQ see:
SARS-CoV-2 Antibodies (NCVIGG, NCVIGQ)[NCVIGB], The qualitative detection of anti-Nucleocapsid IgG (NCVIGG) and the quantitative detection of anti-Spike IgG (NCVIGQ) antibodies.
For all questions, contact Client Support Services (available 24/7):
Phone: (206) 520-4600 or (800) 713-5198
Fax: (206) 520-4903
The test order requisition is available online
- SARS-CoV-2 (COVID-19) Antibody, SARS-CoV-2 (COVID-19) Serology
- Reference Range
- See individual components
- Ref. Range Notes
Per manufacture’s package insert protective level is ≥50.0 AU/mL.
Ordering & Collection
- Specimen Type
Preferred: 5 mL blood in GOLD SST tube.
Also Acceptable: Orange RST, pearl PPT, serum from red top, plasma from EDTA tube.
- Handling Instructions
- Spin within 24 hours and prior to shipment.
- sample is stable for 7 days at 2-8°C once separated from a clot or red blood cells, or in a gel separator tube.
- If testing will be delayed more than 7 days store at -20°C or colder.
Send Specimens to:
Department of Laboratory Medicine
Virology- Covid Testing Lab
1601 Lind Ave SW
Renton, WA 980573356
-Tel: (206) 543-3572
requested: Entire sample
minimum: 0.5 mL serum
Centrifuge GOLD SST tube and route to Eastlake Virology (EVIR rack 81).
Centrifuge RED TOP or EDTA tube and aliquot serum/plasma into plastic aliquot tube. Route to Eastlake Virology (EVIR rack 81).
Stability: Sample stable off the clot, red blood cells, or separator gel for 7 days at 2-8°C. If testing will be delayed more than 7 days store at -20°C or colder.
- Transport Temperature
- LIS Dept Code
- Virology, Eastlake (EVIR)
- Performing Location(s)
Other Virology, Renton
1601 Lind Ave SW
Renton, WA 98057
- Available STAT?
Billing & Coding
- CPT codes