Lupus Anticoagulant, DRVVT
General Information
- Lab Name
- Lupus Anticoagulant, DRVVT
- Lab Code
- LUPAC
- Epic Name
- (not orderable in Epic)
- Description
This Lupus Anticoagulant test uses Russell's viper venom to directly activate factors V and X, bypassing the tissue factor pathway and the contact and antihemophilic factor of the intrinsic pathway. The ratio of clotting times with excess phospholipid to that without excess phospholipid is used to determine the presence of lupus inhibitor in the plasma. This test will be added by the laboratory reflexively if Hexagonal Phospholipid assay is negative with prolonged PTT above 40 seconds.
For patients on Xa inhibitors (Apixaban, Rivaroxaban, Edoxaban), order Hexagonal Phospholipid assay (HEXPI) instead.
- Components
Interpretation
- Method
Clot-based
- Reference Range
-
Units: ratio
Female Male Unknown Age Range Age Range Age Range 0-98y 0.00-1.30 0-98y 0.00-1.30 0-98y 0.00-1.30 99y- 99y- 99y- Effective date: 11/03/2014
- Interferences and Limitations
Patients on direct oral anticoagulants (Bivalirudin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban) have prolonged clotting time with the DRVVT assay and may give false positive results depending on the drug concentration in the plasma.
Ordering & Collection
- Specimen Type
Processing
- Receiving Instructions
- Misc Sendout
Performance
- Lab Department
- Coagulation(COAG)
- Frequency
- Available STAT?
- Performing Location(s)
-
HMC Coagulation, Special
206-520-4600325 9th Ave, Rm # GWH-47, Seattle, WA 98104-2420
Billing & Coding
- CPT Codes
- 85613x2
- LOINC
- 18720-3
- Interfaced Order Code
- UOW2923
- Interfaced Result Code
- UOW2923