Factor X Activity, Chromogenic

General Information

Lab Name: Factor X Activity, Chromogenic
Lab Code: CHRF10
Epic Ordering: Factor X Activity, Chromogenic
Description: The presence of any Factor 10 inhibitor like Apixaban (Eliquis), Rivaroxaban (Xarelto), Edoxaban (Savaysa), Unfractionated Heparin or Low Molecular Weight Heparin in a patient sample may affect this test causing an underestimation of the Factor 10 activity.

This test is not affected by lupus inhibitors or direct thrombin inhibitors and may be useful for monitoring warfarin in patients with lupus inhibitors or receiving direct thrombin inhibitors that might interfere with prothrombin time testing.

This test may also be useful to determine Factor 10 Activity Deficiency in patients with Amyloidosis.
Synonyms: F10 Lupus Inhibitor, Factor 10 Lupus Inhibitor, Factor X Lupus Inhibitor, Functional Factor 10

Method

Chromogenic

Reference Range

Units: %

Female		Male
Age	Range	Age	Range
11y-	50-150	11y-	50-150

Ref. Range Notes

CHRF10 of 25% to 35% is equivalent to INR 2-3.5 in a patient on warfarin.

Specimen Type: Blood
Collection: 3 or 5 mL BLUE TOP (CITRATE) tube
Handling Instructions: The lab MUST process the specimen within 4 hours of collection.
Quantity: requested: Entire Sample
minimum: 1 mL citrated plasma

Processing: UW-MT Instructions: Take entire sample to the Coagulation lab for processing.

HMC Instructions: Take entire sample to the Coagulation lab for processing. HMC Coagulation lab will process and freeze plasma sample for transport to UW-MT

Outside Laboratories: Centrifuge for 10 minutes, remove plasma & respin plasma for another 10 minutes. Remove plasma within 4 hours of collection. Freeze plasma (minimum 1.0 mL) @ -20°C to -80°C. Send Frozen on dry ice.

Unacceptable: Hemolyzed samples

LIS Dept Code

Coagulation (COAG)

Performing Location(s)

UW-MT	Coagulation 206-520-4600 Clinical Lab, Room NW220, University of Washington Medical Center, 1959 NE Pacific street, Seattle, WA 98195

Frequency

Daily

Available STAT?

Yes, daily 8AM - 8PM. for other times contact the Lab Medicine Resident on call for approval.