This test is for a single gene selected from the BROCA, ColoSeq™, and Megalencephaly panels, which must be clearly indicated in the space provided on the requisition. Additional single gene testing can be ordered via UW OncoPlex Single Gene [OPG].
For the complete list of genes, see the following pages:
This test uses next-generation sequencing to detect most mutations in the gene tested. Mutations in these genes are associated with hereditary cancer risk and megalencephaly syndromes. The assay completely sequences all exons, non-repetitive introns, and flanking regions of these genes AND detects large deletions and duplications.
Requisition Form and Ordering Instructions
1. Fill out a Genetics Requisition Form
Providers with access to the UW implementation of Epic (i.e., FHCC, HMC, SCCA, UWMC, UWNW) may order this test using the order "UW Genetics and Solid Tumor Test Request."
2. Check "Single Gene Analysis"
3. Indicate specific gene/genes desired in the space provided
Genetics Preauthorization Form (preauthorization is only done for providers who are external to the UW system)
Code | Name |
---|---|
SGNGS | Single Gene Analyzed |
SGNRE | Single Gene Result |
SGNIN | Single Gene Interpretation |
SGNCH | Single Gene Clinical History |
SGNMT | Single Gene Methods |
Next-generation sequencing.
Sequences are aligned to the human genome reference (hg19). Test performed by targeted capture for listed genes followed by next-generation sequencing with Illumina technology. This test was developed and its performance characteristics determined by the University of Washington Department of Laboratory Medicine. It has not been cleared or approved by the US Food and Drug Administration. This laboratory is certified under the Clinical Laboratory Improvement Amendments (CLIA) as qualified to perform high complexity clinical laboratory testing. This test is used for clinical purposes. It should not be regarded as investigational or for research.
No mutations detected.
BLOOD:
Preferred: 10 mL whole blood in LAVENDER TOP EDTA tube.
Also acceptable: YELLOW TOP ACD tube, purified DNA from peripheral blood or cultured cells.
SALIVA:
Contact laboratory for validated collection kit.
Requisition Form and Ordering Instructions
1. Fill out a Genetics Requisition Form
Providers with access to the UW implementation of Epic (i.e., FHCC, HMC, SCCA, UWMC, UWNW) may order this test using the order "UW Genetics and Solid Tumor Test Request."
2. Check "Single Gene Analysis"
3. Indicate specific gene/genes desired in the space provided
Genetics Preauthorization Form (preauthorization is only done for providers who are external to the UW system)
Ship specimen at room temperature for overnight delivery.
Blood specimens can be held for up to 7 days before shipping if refrigerated.
Ship specimens to:
UW MEDICAL CENTER
LABORATORY MEDICINE - GENETICS LAB
1959 NE PACIFIC ST, ROOM NW220
SEATTLE, WA 98195-7110
Blood: Refrigerate whole blood
Unacceptable Conditions: Frozen or clotted specimens
Stability (collection to initiation of testing): Ambient: 5 days; Refrigerated: 7 days; Frozen: Unacceptable
Purified DNA: Refrigerate DNA specimens. Frozen is acceptable.
Saliva:
Contact laboratory for validated collection kit.
UW-MT |
Genetics
Attention: Genetics Lab Tel: 206-598–6429 M–F (7:30 AM–4:00 PM) Tel (EXOME only): 206-543-0459 |
Faculty |
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For additional test/billing information, see following page: Single Gene CPT codes.
For pricing information, contact Client Support Services 206-520-4600 or 800-713-5198.
Billing and Insurance Pre-Authorization
We offer insurance pre-authorization services (preauthorization is only done for providers who are external to the UW system).
Email: gpab@uw.edu or call 1-855-320-4869 for more information.