Immunoglobulin D
General Information
- Lab Name
- Immunoglobulin D
- Lab Code
- RIGD
- Epic Name
- Immunoglobulin D
- External Test Id
- IGD
- Description
Useful For:
-
Providing information on the humoral immune status
-
Identifying an IgD monoclonal gammopathy
-
- Synonyms
- IGD, IgD, Immune Competence, Immunoglobulin D
- Components
Interpretation
- Method
Turbidimetry
- Reference Range
-
Units: mg/dL
Female Male Age Range Age Range 0- 0-10 0- 0-10 Effective date: 01/03/2006
- Ref. Range Notes
Interpretation: The physiologic significance of serum IgD concentration is unclear and in many normal persons serum IgD is undetectable.
Increased concentrations may be due to polyclonal (reactive) or monoclonal plasma cell proliferative processes.
A monoclonal IgD protein is present in 1% of patients with myeloma. Monoclonal IgD proteins are often in low concentrations and do not have a quantifiable monoclonal protein on serum protein electrophoresis. However, the presence of an IgD monoclonal protein is almost always indicative of a malignant plasma cell disorder such as multiple myeloma or primary amyloidosis.
- Interferences and Limitations
Cautions: An elevated IgD cannot be taken as evidence for a monoclonal IgD protein. PEISO / Protein Electrophoresis and Isotype, Serum should be performed to distinguish between a polyclonal and monoclonal IgD.
Ordering & Collection
- Specimen Type
- Blood
- Collection
-
3 mL blood in RED TOP or SST tube
- Handling Instructions
Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial. Refrigerated serum.
Stability: Refrigerated (preferred): 28 days; Frozen: 28 days; Ambient: 21 days.
Reject Due To: Gross lipemia, heat-inactivated specimen. Gross hemolysis and gross icterus specimens are accepted.
- Quantity
-
Requested: 1 mL serum
Minimum: 0.5 mL serum
Processing
- Receiving Instructions
Centrifuge sample and transfer serum to a separate plastic vial. Refrigerated serum.
Sendouts, order Mayo Test: IGD.
Stability: Refrigerated (preferred): 28 days; Frozen: 28 days; Ambient: 21 days.
Reject Due To: Gross lipemia, heat-inactivated specimen. Gross hemolysis and gross icterus specimens are accepted.
- Misc Sendout
Performance
- Lab Department
- Sendouts Mayo Lab (RF)(MARF)
- Frequency
- Performed: Monday, Wednesday, Friday. Report available: 3-12 days.
- Available STAT?
- No
- Performing Location(s)
-
Sendout Mayo Clinic Laboratories
800-533-1710200 First Street Southwest
Rochester, MN 55901
Billing & Coding
- CPT Codes
- 82784
- LOINC
- 2460-4
- Interfaced Order Code
- UOW1967
- Interfaced Result Code
- UOW1967