Heme Single Gene by NGS

General Information

Lab Name

Heme Single Gene by NGS

Lab Code

HOTSGH

Epic Name

Heme Single Gene Sequencing

Description

The Heme Single Gene by NGS (HOTSGH) assay is intended to test a single gene selected from the Heme Amplicon panel. See synonyms field above for the list of offered genes. The regions of the genes included are amplified using amplification technology and sequenced on an Illumina instrument to detect single nucleotide variants, insertions, and deletions. This test is designed to detect somatic mutations in the setting of neoplasia, and is not designed to detect germline (heritable) mutations.

Synonyms

11-17, 14, 15, 16), 17), 26, 27), 3, 6), 6), ASXL1 (CDS), CBL (CDS), CSF3R (Exons 14, DNMT3A (CDS), EZH2 (Exons 15-20), FBXW7 (CDS), FGFR1 (Exons 4, FLT3 (p.D835H), GATA1 (Exons 2-3), GATA2 (Exons 3-5), Hotspot, HRAS (Exon 1-2), IDH1( p.R132), IDH2 (Exon 4), JAK2 (Exon 12, KIT (8-18), KMT2A (CDS), KRAS (CDS), MAP2K1 (Exons 2, MPL (Exon 10), MYD88 (Exon 3-5), next-generation sequencing, NGS, NOTCH1 (Exons 20, NPM1 (Exon 12), NRAS (CDS), partial 18), PDGFRA (Exons 12-18), PHF6 (CDS), PTEN (CDS), RB1 (CDS), RUNX1 (Exon 4-8), SF3B1 (Exon 14-16), single gene, SRSF2 (Exon 1), STAG2 (CDS), STAT3 (Exons 20-21), TET2 (CDS), TP53 (CDS), U2AF1 (Exons 2, WT1 (CDS), ZRSR2 (CDS)

Components

Code	Name
SGHSD	Heme Gene Specimen Description
SGHRES	Heme Gene Result
SGHINT	Heme Gene Interpretation
SGHM	Heme Gene Method