Anti Endomysial, IgA (by IFA)
General Information
- Lab Name
- Anti Endomysial, IgA
- Lab Code
- AEMYA
- Epic Ordering
- Anti Endomysial, IgA
- Description
The presence of IgA endomysial autoantibodies by indirect immunofluorescence is suggestive of active gluten sensitive enteropathies such as celiac disease. Results are primarily useful for diagnosis; they may also be used for monitoring response to treatment with a gluten-free diet, but results are semi-quantitative.
- References
Bürgin-Wolff, et al., Antigliadin and antiendomysium antibody determination for coeliac disease. Arch Dis Child. (1991) 66:941.
- Synonyms
- Celiac, Celiac Ab, Endomysium, Sprue
Interpretation
- Method
Indirect immunofluorescence (IFA) using INOVA monkey esophagus tissue to detect IgA autoantibodies.
- Reference Range
-
Female Male Age Range Age Range 0- Negative [NRN] 0- Negative [NRN] Effective date: 04/01/2010
- Ref. Range Notes
Established by testing healthy blood donors during method validation.
- Interferences and Limitations
Anti-smooth muscle antibodies may obscure endomysial staining. The test cannot be used for patients with IgA deficiency.
- References
Bürgin-Wolff, et al., Antigliadin and antiendomysium antibody determination for coeliac disease. Arch Dis Child. (1991) 66:941.
- Guidelines
Ordering & Collection
- Specimen Type
- Blood
- Collection
-
3 mL blood in RED TOP or SST tube
- Handling Instructions
Instructions for Outside Clients: Freeze serum at -20°C
Stability: Room Temperature: up to 8 hours; Refrigerated: 2 days; Frozen at -20°C: Long Term
- Quantity
-
requested: 1 mL serum
minimum: 0.3 mL serum
Processing
- Processing
Freeze serum at -20°C
Note: If Anti Endomysial is requested without specifying method (i.e. IFA or EIA), then order: AEMYA
Note2: AEMYA may be reflexively added on to CELRP orders if indicated.
Stability: Room Temperature: up to 8 hours; Refrigerated: 2 days; Frozen at -20°C: Long Term
Performance
- LIS Dept Code
- Immunology (IMM)
- Performing Location(s)
-
UW-MT Immunology
206-520-4600Clinical Lab, Room NW220,
University of Washington Medical Center,
1959 NE Pacific street, Seattle, WA 98195 - Frequency
- Wednesday, Friday. Negative results same day. Positive results on next run.
- Available STAT?
- No
Billing & Coding
- CPT codes
- 86231
- LOINC
- 46126-9
- Interfaced Order Code
- UOW866
- Interfaced Result Code
- UOW866