Insulin Antibody (Sendout)
General Information
- Lab Name
- Insulin Antibody (Sendout)
- Lab Code
- RINSG
- Epic Name
- Insulin Antibody (Sendout)
- External Test Id
- FINAB
- Description
Useful For:
- Predicting the future development of type 1 diabetes in asymptomatic children, adolescents, and young adults, when used in conjunction with family history, human leukocyte antigen-typing, and other autoantibodies, including glutamic acid decarboxylase (GAD65) and islet cell antigen 2 (IA-2) antibodies
- Differential diagnosis of type 1 versus type 2 diabetes
- Evaluating diabetics with insulin resistance in patients with established diabetes (type 1 or type 2)
- Investigation of hypoglycemia in nondiabetic subjects
***Ordering Note: Effective 08/18/2025, this test is offline at Mayo Clinic Laboratories. Samples will be temporarily forwarded by Mayo to Esoterix Endocrinology and reported under Reference Laboratory Test 1 (SEND1) due to accompanying change in method and reference range.***
- References
- Mayo Clinical & Interpretive Information: Insulin Autoantibodies (IAA)
- Synonyms
- Anti-Insulin, FINAB, Human Insulin, INAB, Insulin Ab
- Components
-
Code Name RINAB Insulin Antibody
Interpretation
- Method
Esoterix Laboratory Method: Insulin-I125 binding capacity
- Reference Range
- See individual components
- Ref. Range Notes
Esoterix Laboratory Reference Values (for samples arriving at Mayo after 08/17/25):
Negative: <5.0 uU/mL Positive: > or = 5.0 uU/mL - Interferences and Limitations
Cautions: This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held 1 week and assayed if sufficiently decayed, or canceled if radioactivity remains.
Ordering & Collection
- Specimen Type
- Blood
- Collection
-
5 mL blood in a RED TOP tube or GOLD SST
- Handling Instructions
Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial. Freeze serum at -20°C while awaiting shipment. Transport on dry ice.
Stability: Frozen: Preferred; Refrigerated: 72 hours; Ambient: 72 hours.
Reject Due To: Radioactive isotopes administered 24 hours prior to venipuncture. Thawing: cold okay; warm reject.
- Quantity
-
Requested: 0.5 mL serum
Minimum: 0.2 mL serum (Note: This volume does not permit repeat analysis.)
Processing
- Receiving Instructions
Centrifuge sample and transfer serum to a separate plastic vial. Freeze serum at -20°.
Sendouts:
- Order Mayo Test: FINAB
- Interfaced: No
Stability: Frozen: Preferred; Refrigerated: 72 hours; Ambient: 72 hours.
Reject Due To: Radioactive isotopes administered 24 hours prior to venipuncture. Thawing: cold okay; warm reject.
- Misc Sendout
Performance
- Lab Department
- Sendouts Mayo Lab (RF)(MARF)
- Frequency
- Performed: Monday through Sunday. Report Available: 9-16 days from sample receipt at Mayo Clinic Laboratories.
- Available STAT?
- No
- Performing Location(s)
-
Sendout Mayo forwards to Esoterix Endocrinology, Inc.
800-533-17104301 Lost Hills Road
Calabasas Hills, CA 91301
Billing & Coding
- CPT Codes
- 86337
- LOINC
- 60463-7
- Interfaced Order Code
- UOW2419