Clonazepam and 7-Aminoclonazepam (Sendout)

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General Information

Lab Name
Clonazepam and 7_Aminoclonazepam
Lab Code
RCLONG
Epic Name
Clonazepam and 7_Aminoclonazepam (Sendout)
External Test Id
CZPS
Description

Useful For:

  • Assessing patient compliance
  • Monitoring for appropriate therapeutic level
  • Assessing clonazepam toxicity

Collection Timing: Draw blood immediately before next scheduled dose (minimum 12 hours after last dose).

***Note: Test temporarily unavailable at Mayo Clinic Laboratories as of 12/14/2023 due to instrument issues. Orders will be forwarded to NMS Labs for Clonazepam and Metabolite, Serum/Plasma and reported under Reference Laboratory Test 1 (SEND1) until testing resumes.***

Synonyms
7-Aminoclonazepam, Clonopin, CZPS, Klonopin, Nitrozepane, Rivotrol
Components
Code Name
RCLON Clonazepam
R7ACLN 7_Aminoclonazepam

Interpretation

Method

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reference Range
See individual components

Ordering & Collection

Specimen Type
Blood
Collection

4 mL blood in a RED TOP tube

Unacceptable: Any other tube type, including gel/SST tubes

Handling Instructions

Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial within two hours of collection. Refrigerate serum.

Stability: Refrigerated (preferred): 14 days; Frozen: 30 days; Ambient: Unacceptable.

Reject Due To: Gross icterus. Gross hemolysis, gross lipemia are acceptable.

Quantity
Requested: 2 mL serum
Minimum: 0.7 mL serum

Processing

Receiving Instructions

Centrifuge sample and transfer serum to a separate plastic vial within two hours of collection. Refrigerate serum.

Sendouts (Temporary Workflow):

  • Batch the outgoing order on the interface.
  • Add Mayo Test: FCLMS and remove obsolete code CZPS.

Stability: Refrigerated (preferred): 14 days; Frozen: 30 days; Ambient: Unacceptable.

Reject Due To: Gross icterus. Gross hemolysis, gross lipemia are acceptable.

Misc Sendout

Performance

Lab Department
Sendouts Mayo Lab (RF)(MARF)
Frequency
Performed: Monday through Sunday. Report Available: 7-11 days from sample receipt at the performing lab.
Available STAT?
No
Performing Location(s)
Sendout Mayo forwards to NMS Labs
800-533-1710

200 Welsh Road
Horsham, PA 19044

Formerly: Mayo forwards to National Medical Services, Inc. (MAYNMS)

Billing & Coding

CPT Codes
80299
LOINC
18719-5
Interfaced Order Code
UOW3304