SARS-CoV-2 Antibody, IgG Immune Status (Nucleocapsid & Quant. anti-Spike)

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General Information

Lab Name
SARS CoV 2 Immune Status
Lab Code
NCVIGB
Epic Ordering
SARS-CoV-2 Immune Status
Description

A battery of tests to determine SARS-CoV-2 immune status:

  1. The Abbott Architect SARS-CoV-2 IgG assay, run under an emergency use authorization from the FDA, is a qualitative test designed to detect IgG antibodies to the nucleocapsid protein of SARS-CoV-2.
  2. The Abbott Architect SARS-CoV-2 IgG II assay, run under an emergency use authorization from the FDA, is a quantitative test designed to detect IgG antibodies to the spike protein of SARS-CoV-2 in serum and plasma. Results are reported as AU/mL. Per manufacture’s package insert protective level is ≥50.0 AU/mL.

Ordering: We are pleased to perform serology testing for all patients who have a valid provider order. We recommend outside providers arrange to have their patients' blood drawn at their usual clinical draw sites and sent to the lab, preferably after contacting Client Support Services at commserv@uw.edu to facilitate testing.

For patients who do not regularly seek care within UW Medicine, our phlebotomists at the University of Washington Medical Center-Northwest Campus (UWMC-NW) and UWMC-NW Outpatient Medical Center (OPMC) located on Meridian Ave. N. are able to perform blood draws for testing with a valid provider order.

For ordering individual battery components:

NCVIGG see SARS CoV 2 Nucleocapsid Antibody, IgG [NCVIGG]

NVCIGQ see SARS CoV 2 Spike Antibody, IgG [NCVIGQ]

For all questions, contact Client Support Services (available 24/7):

Phone: (206) 520-4600 or (800) 713-5198
Fax: (206) 520-4903
Email: commserv@uw.edu

The test order requisition is available online

Synonyms
SARS-CoV-2 (COVID-19) Antibody, SARS-CoV-2 (COVID-19) Serology
Components

Interpretation

Method

Chemiluminesence

Reference Range
See individual components
Ref. Range Notes

Per manufacture’s package insert, the Abbott Architect SARS-CoV-2 IgG II assay designed to detect IgG antibodies to the spike protein of SARS-CoV-2 the protective level is ≥50.0 AU/mL.

Guidelines

Ordering & Collection

Specimen Type
Collection

Preferred: 5 mL blood in GOLD SST tube.
Also Acceptable: Orange RST, pearl PPT, serum from red top, plasma from EDTA tube.

Handling Instructions

Spin within 24 hours and prior to shipment.
sample is stable for 7 days at 2-8°C once separated from a clot or red blood cells, or in a gel separator tube.
If testing will be delayed more than 7 days store at -20°C or colder.

UW Medicine
Department of Laboratory Medicine
Virology- Covid Testing Lab
1601 Lind Ave SW
Renton, WA 98057-3356
Tel: (206) 685-6656 opt 4

Quantity
requested: Entire sample
minimum: 0.5 mL serum

Processing

Processing

Centrifuge GOLD SST tube and route to Virology Central Lab (Renton)..

Centrifuge RED TOP or EDTA tube and aliquot serum/plasma into plastic aliquot tube. Route to Virology Central Lab (Renton).

Stability: Sample stable off the clot, red blood cells, or separator gel for 7 days at 2-8°C. If testing will be delayed more than 7 days store at -20°C or colder.

Performance

LIS Dept Code
Central Lab Virology (RVIR)
Performing Location(s)
CL Virology, Renton
206-685-6656

1602 Raymond Ave SW

Renton, WA 98057-3356

206-685-6656 opt 4
Frequency
Mondays and Fridays, with results available on the same day.
Available STAT?
No

Billing & Coding

CPT codes
86413, 86769
LOINC
94504-8
Interfaced Order Code
UOW4193