HSV Acyclovir Drug Resistance by Sanger Sequencing

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General Information

Lab Name
HSV Acyclovir Drug Resistance
Lab Code
HSVDR
Epic Ordering
HSV Acyclovir Drug Resistance
Description

HSV Type 1 and HSV Type 2 Drug Resistance to Acyclovir in the Thymidine Kinase (UL23 only) gene detected by Sanger Sequencing.

Synonyms
Acyclovir, Drug Resistance, HSV, Sanger
Components

Interpretation

Method

Sanger Sequencing

Reference Range
See individual components

Ordering & Collection

Specimen Type
Swabs, Blood, Spinal Fluid, BAL, Eye Fluid
Collection

Collect ONE of the following:

  • Swabs in 1.5 mL VTM
  • 3 mL blood in LAVENDER, RED, SST, PPT tube
  • 1 mL Spinal Fluid
  • 1 mL BAL

Unacceptable: GREEN TOP, Extracted nucleic acid from an outside laboratory.

Handling Instructions
Quantity
requested: 1.5 mL plasma/serum/CSF/BAL or swabs in 1.5 mL VTM
minimum: 1 mL plasma/serum/CSF/BAL or swabs in 1 mL VTM

Processing

Processing

Blood: Centrifuge tube within 24 hours of collection & aliquot serum/plasma. Freeze at -20°C.

CSF: Freeze within 2 hours of collection or ship immediately at 4°C. If CSF has cells, centrifuge & aliquot clear CSF-Freeze at -20°C.

Outside Laboratory: If no freezer available, ship at 4°C. Ship time not to exceed 48 hrs. Do not freeze/thaw. If frozen, ship with Dry Ice.

Performance

LIS Dept Code
Virology, Eastlake (EVIR)
Performing Location(s)
Other Virology, Molecular
206-685-6656

Virology Laboratory, Ste 320
1616 Eastlake Ave E.
Seattle, WA 98102

Frequency
Available STAT?
No

Billing & Coding

CPT codes
87900
LOINC
29578-2
Interfaced Order Code
UOW3692