Fondaparinux Activity Assay
General Information
- Lab Name
- Fondaparinux Activity Assay
- Lab Code
- FNDXT
- Epic Name
- Fondaparinux Activity Assay
- Description
- Synonyms
- Arixtra, Fondaparinux assay
- Components
Interpretation
- Method
This method determines a factor Xa inhibitor level by measuring the inhibition of factor Xa cleavage of a chromogenic substrate. Because no exogenous antithrombin is added in this assay, and because antithrombin plays a significant role in factor Xa inhibition with heparin, low molecular weight heparin, or fondaparinux, patients with lower antithrombin levels (<70%) may demonstrate lower anti-Xa activity.
- Reference Range
- Units: mcg/mL
- Ref. Range Notes
No therapeutic range has been established. For more information, see link above ("UW Medicine Anticoagulation Services")
Ordering & Collection
- Specimen Type
- Blood
- Collection
-
2mL, 3mL or 5 mL BLUE TOP tube
- Approval Required
- LMR approval required if to be ordered as STAT
- Quantity
-
Requested: entire sample
Minimum: 2 mL Blue top tube
Processing
- Receiving Instructions
Take entire sample to Coagulation. UW-MT Coagulation will Process whole blood samples if arrive in Coag lab within 4 hrs of draw. This is not to be ordered as STAT, Call LMR for approval if so.
Outside Laboratories and HMC Coagulation: Centrifuge sample 10 minutes at 2500g, remove plasma, respin plasma 10 minutes at 2500g, freeze upper ¾ plasma and transport to UW-MT Coagulation Lab frozen.
- Misc Sendout
Performance
- Lab Department
- Coagulation(COAG)
- Frequency
- Daily
- Available STAT?
- NO
- Performing Location(s)
-
UW-MT Coagulation
206-520-4600Clinical Lab, Room NW220,
University of Washington Medical Center,
1959 NE Pacific street, Seattle, WA 98195
Billing & Coding
- CPT Codes
- 80299
- LOINC
- 74217-1
- Interfaced Order Code
- UOW2554
- Interfaced Result Code
- UOW2554