Gynecologic Oncology (GYNPTH) Pathways
These four pathways are composed of paired tumor-germline testing for patients with gynecological cancers, following the UWMC Gynecological Oncology Pathways. The pathways include one or more tests from the following list, as determined by the agreed-upon diagnostic pathway: BROCA Paired Tumor Panel [BROCOP], targeted KRAS Mutations (DNA) [KRAS], BRAF Mutations [BRAF], MLH1 Promoter Hypermethylation [MLH1MT], Microsatellite Instability [MSI], UW OncoPlex Single Gene [OPG], UW OncoPlex Cancer Gene Panel [OPX], PDL1 IHC (send out).
These diagnostic pathways are defined by tumor type. See links below for testing specifics for each pathway:
- Ovarian, Fallopian, Peritoneal Pathway
- Primary Endometrial Carcinoma Pathway
- Recurrent + Metastatic Endometrial Carcinoma or Rare Tumor Pathway
- Recurrent + Metastatic Cervical, Vulvar, Vaginal Pathway
Peripheral blood for Tumor Test Comparator Sample [OPCOMP] should be submitted.
Tumor tissue will be acquired by the laboratory.
The test order Gynecological Oncology Pathway [GYNPTH] will be initiated per the tumor type Gynecological Oncology Pathway (see above for diagnostic pathway details).
Requisitions and Contact Information
Instructions: Complete the appropriate requisition(s) and submit according to requisition instructions. The laboratory will start acquiring tissue when a completed requisition is received.
For pathway specific questions, including ordering help, please contact: firstname.lastname@example.org.
For pre-authorization questions, please contact: email@example.com.
For pre-analytical specimen type questions, please contact: firstname.lastname@example.org.
Fax number: 206.598.0304
|BRAF||BRAF Mutations||Tumor Tissue, Purified DNA, accompanied ...|
|BROCOP||BROCA Paired Tumor Panel||Formalin-Fixed Paraffin Embedded Tumor T...|
|KRAS||KRAS Mutations (DNA)||Tumor Tissue, Purified DNA, accompanied ...|
|MSI||Microsatellite Instability||Tumor Tissue, Purified DNA, Bone Marrow,...|
|MLH1MT||MLH1 Promoter Hypermethylation|
|OPCOMP||Tumor Test Comparator Sample||Peripheral blood|
|OPX||UW OncoPlex Cancer Gene Panel||Tumor Tissue, Purified DNA, Bone Marrow,...|
|OPG||UW OncoPlex Single Gene||Tumor Tissue, Purified DNA, Bone Marrow,...|
Last updated 2022-12-01T16:54:03.134127+00:00