Heparin Induced Platelet Antibody

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General Information

Lab Name
Heparin Induced Platelet Antibody
Lab Code
HIPAB
Epic Ordering
Heparin Induced Platelet Antibody
Description
The HIPAB or Heparin Induced Platelet Ab panel is NOT reflexive for the Seratonin Release Assay. NOTE: The HITRP or HIT Reflexive Panel IS reflexive for the Seratonin Release Assay. For HMC/UW-MT Inpatients, suggest ordering Heparin Induced Thrombocytopenia Reflexive Panel (HITRP). When the HITRP is ordered the Seratonin Release Assay (RSRAG) will be added reflexively with any positive Heparin Induced Platelet Antibody (HIPA) component test. See "HIT Reflexive Panel" in the Laboratory Test Catalog for sample and other information. Assay interference: heparin at a level of >1.0 IU/mL in a test sample will interfere with the HIPA assay and will cause false negative results.
Synonyms
Heparin Induced Antibody, Heparin Induced Thrombocytopenia, Heparin-PF4 antibody, HIPA, HIT Antibody, HIT Elisa, PF4 Heparin Antibody
Components

Interpretation

Method
EIA
Reference Range
See individual components
Ref. Range Notes
Critical Value: Positive
Strong Positive, elevated thrombotic risk

Ordering & Collection

Specimen Type
Blood
Collection
5 mL BLUE TOP (CITRATE) tube
Note: collect both BLUE TOP and RED TOP for HIT Panel (see HITRP)
Handling Instructions
Lab must process specimen within 6 hours of collection.
Quantity
requested: 1 mL plasma
minimum: 0.5 ml plasma

Processing

Processing
Take specimen to Coag to process

Outside Laboratories: Centrifuge for 10 minutes, remove plasma & respin plasma for another 10 minutes. Remove plasma within 6 hours of collection. Freeze plasma (minimum 0.5 mL) @ -20°C to -80°C. Send Frozen on dry ice.

Performance

LIS Dept Code
Coagulation (COAG)
Performing Location(s)
UW-MT Coagulation
206-520-4600

Clinical Lab, Room NW220,
University of Washington Medical Center,
1959 NE Pacific street, Seattle, WA 98195

Frequency
Daily Samples that arrive in the UW-MT Coagulation lab section by noon will be run that same day.
Available STAT?
with Lab Medicine Resident approval only

Billing & Coding

CPT codes
86022
LOINC
34701-3
Interfaced Order Code
UOW2817